open access

Vol 13, No 7 (2006): Folia Cardiologica
Review paper
Published online: 2006-09-15
Get Citation

The cardiovascular implications of omega-3 fatty acids

Robert C. Block, Thomas A. Pearson
Folia Cardiol 2006;13(7):557-569.

open access

Vol 13, No 7 (2006): Folia Cardiologica
Review articles
Published online: 2006-09-15

Abstract

Nutrition is an important factor in the primary and secondary prevention of cardiovascular disease. Cardiovascular disease is the leading cause of death in North America and the world. Observational studies have generally favoured a beneficial role of n-3 fatty acids in the prevention of heart disease, especially in the prevention of sudden cardiac death. The results of more recent randomised controlled studies, however, have made conclusions regarding the benefit more controversial, with the suggestion of possible harm with fish oil supplementation to those with diagnosed cardiovascular disease.
We provide an overview of the results of studies to date and introduce the controversial topics of the omega-6/omega-3 ratio, the public’s concerns regarding ingestion of mercury from marine n-3 sources and the potential role of highly bioactive n-3 metabolites in the process of atherosclerosis. We also provide some general guidelines for the ingestion of n-3 fatty acids that may help clinicians and patients make informed decisions.

Abstract

Nutrition is an important factor in the primary and secondary prevention of cardiovascular disease. Cardiovascular disease is the leading cause of death in North America and the world. Observational studies have generally favoured a beneficial role of n-3 fatty acids in the prevention of heart disease, especially in the prevention of sudden cardiac death. The results of more recent randomised controlled studies, however, have made conclusions regarding the benefit more controversial, with the suggestion of possible harm with fish oil supplementation to those with diagnosed cardiovascular disease.
We provide an overview of the results of studies to date and introduce the controversial topics of the omega-6/omega-3 ratio, the public’s concerns regarding ingestion of mercury from marine n-3 sources and the potential role of highly bioactive n-3 metabolites in the process of atherosclerosis. We also provide some general guidelines for the ingestion of n-3 fatty acids that may help clinicians and patients make informed decisions.
Get Citation

Keywords

omega-3 fatty acids; omega-6 fatty acids; n-6/n-3 ratio; omacor; omega-3 index

About this article
Title

The cardiovascular implications of omega-3 fatty acids

Journal

Cardiology Journal

Issue

Vol 13, No 7 (2006): Folia Cardiologica

Article type

Review paper

Pages

557-569

Published online

2006-09-15

Bibliographic record

Folia Cardiol 2006;13(7):557-569.

Keywords

omega-3 fatty acids
omega-6 fatty acids
n-6/n-3 ratio
omacor
omega-3 index

Authors

Robert C. Block
Thomas A. Pearson

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: viamedica@viamedica.pl