open access

Vol 14, No 5 (2007)
Review paper
Published online: 2007-08-02
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Brugada syndrome: From diagnosis to treatment

Aneta Kucharczyk-Foltyn, Maria Śnieżek-Maciejewska, Maciej Dymek, Jerzy Sadowski, Marianna Janion
Cardiol J 2007;14(5):429-435.

open access

Vol 14, No 5 (2007)
Review articles
Published online: 2007-08-02

Abstract

Brugada syndrome is electrocardiographically characterised by ST segment elevation in right precordial leads and the occurrence of episodes of polymorphic ventricular tachycardia. It is also associated with a high risk of sudden death, which may be the first manifestation of the disease. Various mutations of SCN5A gene encoding for the cardiac sodium channel are among the proven causes of BS. ICD remains the only treatment for BS of proven efficacy. However, many questions about etiology, underlying mechanisms, safety of asymptomatic patients and treatment options for BS remain unanswered. (Cardiol J 2007; 14: 429-435)

Abstract

Brugada syndrome is electrocardiographically characterised by ST segment elevation in right precordial leads and the occurrence of episodes of polymorphic ventricular tachycardia. It is also associated with a high risk of sudden death, which may be the first manifestation of the disease. Various mutations of SCN5A gene encoding for the cardiac sodium channel are among the proven causes of BS. ICD remains the only treatment for BS of proven efficacy. However, many questions about etiology, underlying mechanisms, safety of asymptomatic patients and treatment options for BS remain unanswered. (Cardiol J 2007; 14: 429-435)
Get Citation

Keywords

Brugada syndrome; SCN5A mutations; implantable cardioverter-defibrillator

About this article
Title

Brugada syndrome: From diagnosis to treatment

Journal

Cardiology Journal

Issue

Vol 14, No 5 (2007)

Article type

Review paper

Pages

429-435

Published online

2007-08-02

Bibliographic record

Cardiol J 2007;14(5):429-435.

Keywords

Brugada syndrome
SCN5A mutations
implantable cardioverter-defibrillator

Authors

Aneta Kucharczyk-Foltyn
Maria Śnieżek-Maciejewska
Maciej Dymek
Jerzy Sadowski
Marianna Janion

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