open access
Microalbuminuria in systolic and diastolic chronic heart failure patients
open access
Abstract
Methods: In a cross-sectional study, we included 72 chronic heart failure patients (NYHA I-III) on standard HF therapy. All patients had an echocardiogram and body composition by vector bioelectric impedance analysis (measured by Body Stat Quad Scan).
Results: The studied population consisted of 64% men at mean age of 62.6 ± 15.1 years. Patients were divided into systolic and diastolic HF groups. Microalbuminuria was observed in 40% of diastolic and 24% systolic HF patients (p = 0.04). Microalbuminuria was present in more patients with volume overload (80 vs. 21.9%, p = 0.002), with a worse phase angle and lower serum albumin (4.7 vs. 5.9° and 3.5 vs. 4.0 mg/dl, p = 0.02) and higher pulmonary arterial pressure compared with patients without microalbuminuria in systolic HF patients. There was no significant association between frequency of microalbuminuria and ejection fraction. In the diastolic HF group, the presence of microalbuminuria was not associated with any known risk factor.
Conclusions: Microalbuminuria was more frequent in diastolic than systolic HF patients. In systolic HF patients microalbuminuria was associated with factors known to be markers of worse prognosis. (Cardiol J 2008; 15: 143-149)
Abstract
Methods: In a cross-sectional study, we included 72 chronic heart failure patients (NYHA I-III) on standard HF therapy. All patients had an echocardiogram and body composition by vector bioelectric impedance analysis (measured by Body Stat Quad Scan).
Results: The studied population consisted of 64% men at mean age of 62.6 ± 15.1 years. Patients were divided into systolic and diastolic HF groups. Microalbuminuria was observed in 40% of diastolic and 24% systolic HF patients (p = 0.04). Microalbuminuria was present in more patients with volume overload (80 vs. 21.9%, p = 0.002), with a worse phase angle and lower serum albumin (4.7 vs. 5.9° and 3.5 vs. 4.0 mg/dl, p = 0.02) and higher pulmonary arterial pressure compared with patients without microalbuminuria in systolic HF patients. There was no significant association between frequency of microalbuminuria and ejection fraction. In the diastolic HF group, the presence of microalbuminuria was not associated with any known risk factor.
Conclusions: Microalbuminuria was more frequent in diastolic than systolic HF patients. In systolic HF patients microalbuminuria was associated with factors known to be markers of worse prognosis. (Cardiol J 2008; 15: 143-149)
Keywords
microalbuminuria; systolic and diastolic heart failure; body composition markers
About this articleTitle
Microalbuminuria in systolic and diastolic chronic heart failure patients
Journal
Issue
Pages
143-149
Published online
2008-02-21
Page views
716
Article views/downloads
1036
DOI
10.5603/cj.21619
Bibliographic record
Cardiol J 2008;15(2):143-149.
Keywords
microalbuminuria
systolic and diastolic heart failure
body composition markers
Authors
Arturo Orea-Tejeda
Eloisa Colín-Ramírez
Thierry Hernández-Gilsoul
Lilia Castillo-Martínez
Marcela Abasta-Jiménez
Enrique Asensio-Lafuente
René Narváez David
Joel Dorantes-García
