open access

Vol 15, No 2 (2008)
Original articles
Published online: 2008-02-21
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Microalbuminuria in systolic and diastolic chronic heart failure patients

Arturo Orea-Tejeda, Eloisa Colín-Ramírez, Thierry Hernández-Gilsoul, Lilia Castillo-Martínez, Marcela Abasta-Jiménez, Enrique Asensio-Lafuente, René Narváez David, Joel Dorantes-García
Cardiol J 2008;15(2):143-149.

open access

Vol 15, No 2 (2008)
Original articles
Published online: 2008-02-21

Abstract

Background: Microalbuminuria is considered a major risk factor predisposing to cardiovascular morbidity and mortality. Microalbuminuria levels in patients with or without diabetes have been associated with a higher risk of chronic heart failure (HF). However, there are limited data regarding prevalence of microalbuminuria in chronic heart failure and its prognostic value. The aim of this study was to assess the occurence of microalbuminuria in chronic heart failure patients as well as its association with clinical, echocardiographic, and body composition markers.
Methods: In a cross-sectional study, we included 72 chronic heart failure patients (NYHA I-III) on standard HF therapy. All patients had an echocardiogram and body composition by vector bioelectric impedance analysis (measured by Body Stat Quad Scan).
Results: The studied population consisted of 64% men at mean age of 62.6 ± 15.1 years. Patients were divided into systolic and diastolic HF groups. Microalbuminuria was observed in 40% of diastolic and 24% systolic HF patients (p = 0.04). Microalbuminuria was present in more patients with volume overload (80 vs. 21.9%, p = 0.002), with a worse phase angle and lower serum albumin (4.7 vs. 5.9° and 3.5 vs. 4.0 mg/dl, p = 0.02) and higher pulmonary arterial pressure compared with patients without microalbuminuria in systolic HF patients. There was no significant association between frequency of microalbuminuria and ejection fraction. In the diastolic HF group, the presence of microalbuminuria was not associated with any known risk factor.
Conclusions: Microalbuminuria was more frequent in diastolic than systolic HF patients. In systolic HF patients microalbuminuria was associated with factors known to be markers of worse prognosis. (Cardiol J 2008; 15: 143-149)

Abstract

Background: Microalbuminuria is considered a major risk factor predisposing to cardiovascular morbidity and mortality. Microalbuminuria levels in patients with or without diabetes have been associated with a higher risk of chronic heart failure (HF). However, there are limited data regarding prevalence of microalbuminuria in chronic heart failure and its prognostic value. The aim of this study was to assess the occurence of microalbuminuria in chronic heart failure patients as well as its association with clinical, echocardiographic, and body composition markers.
Methods: In a cross-sectional study, we included 72 chronic heart failure patients (NYHA I-III) on standard HF therapy. All patients had an echocardiogram and body composition by vector bioelectric impedance analysis (measured by Body Stat Quad Scan).
Results: The studied population consisted of 64% men at mean age of 62.6 ± 15.1 years. Patients were divided into systolic and diastolic HF groups. Microalbuminuria was observed in 40% of diastolic and 24% systolic HF patients (p = 0.04). Microalbuminuria was present in more patients with volume overload (80 vs. 21.9%, p = 0.002), with a worse phase angle and lower serum albumin (4.7 vs. 5.9° and 3.5 vs. 4.0 mg/dl, p = 0.02) and higher pulmonary arterial pressure compared with patients without microalbuminuria in systolic HF patients. There was no significant association between frequency of microalbuminuria and ejection fraction. In the diastolic HF group, the presence of microalbuminuria was not associated with any known risk factor.
Conclusions: Microalbuminuria was more frequent in diastolic than systolic HF patients. In systolic HF patients microalbuminuria was associated with factors known to be markers of worse prognosis. (Cardiol J 2008; 15: 143-149)
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Keywords

microalbuminuria; systolic and diastolic heart failure; body composition markers

About this article
Title

Microalbuminuria in systolic and diastolic chronic heart failure patients

Journal

Cardiology Journal

Issue

Vol 15, No 2 (2008)

Pages

143-149

Published online

2008-02-21

Bibliographic record

Cardiol J 2008;15(2):143-149.

Keywords

microalbuminuria
systolic and diastolic heart failure
body composition markers

Authors

Arturo Orea-Tejeda
Eloisa Colín-Ramírez
Thierry Hernández-Gilsoul
Lilia Castillo-Martínez
Marcela Abasta-Jiménez
Enrique Asensio-Lafuente
René Narváez David
Joel Dorantes-García

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