open access

Vol 15, No 2 (2008)
Original articles
Published online: 2008-02-21
Submitted: 2013-01-14
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Left ventricular systolic and diastolic function in patients with atrioventricular nodal re-entrant tachycardia treated by radiofrequency current ablation

Agata Duszańska, Radosław Lenarczyk, Oskar Kowalski, Witold Streb, Ewa Markowicz-Pawlus, Tomasz Kukulski, Zbigniew Kalarus
Cardiol J 2008;15(2):150-155.

open access

Vol 15, No 2 (2008)
Original articles
Published online: 2008-02-21
Submitted: 2013-01-14

Abstract

Background: The impact of radiofrequency current ablation (RFCA) on left ventricular (LV) systolic and diastolic function in patients with atrioventricular nodal re-entrant tachycardia (AVNRT) is not well established yet.
Methods: The study group consisted of 25 patients (18 W, mean age 43 ± 11) with recurrent episodes of AVRT without any concomitant diseases. The control group was formed of 25 healthy volunteers. In both study and control groups, transthorasic echocardiography (TTE) and Doppler were performed in order to assess LV systolic and diastolic function. In AVNRT syndrome patients, TTE was followed by electrophysiology study and RFCA. TTE was repeated after six months in the study group.
Results: Significant differences were found between the study and control groups with regard to LV systolic (FS - fractional shortening: 37 ± 4 vs. 42 ± 6%, p = 0.001; ESV - end-systolic volume: 19 ± 4 vs. 17 ± 4 ml/m2, p = 0.03; EF - ejection fraction: 55 ± 5 vs. 62 ± 4%, p = = 0.001) and diastolic function (E wave: 69 ± 17 vs. 84 ± 15 cm/s, p = 0.002; E/A: 1.09 ± ± 0.42 vs. 1.38 ± 0.27, p = 0.005; DT - duration difference between A and AR waves: 7 ± 29 vs. -28 ± 13 ms, p = 0.001; DT - deceleration time of E wave: 223 ± 34 vs. 177 ± 27 ms, p = 0.001; IVRT - isovolumic relaxation time: 105 ± 15 vs. 86 ± 11 ms, p = 0.001; E/A while Valsalva manoeuvre: 0.93 ± 0.35 vs. 1.25 ± 0.16, p = 0.001; AR - atrial reversal velocity: 27 ± 7 vs. 14 ± 11 cm/s, p = 0.001) variables. In 6-month follow-up decrease in LVESV (19 ± 4 vs. 17 ± 4 ml, p < 0.03) and increase in EF (55 ± 5 vs. 62 ± 4%, p < 0.001) was noted. Doppler analysis showed an increase in E wave (69 ± 17 vs. 79 ± 20 cm/s, p < 0.02), E/A ratio (1.09 ± 0.42 vs. 1.30 ± 0.27, p < 0.006) and decrease in A wave (68 ± 13 vs. 63 ± 10 cm/s, p < 0.02), DT (223 ± 34 vs. 179 ± 22 ms, p < 0.001), IVRT (105 ± 15 vs. 89 ± 11 ms, p < 0.001) and DT (7 ± 29 vs. -13 ± 28 ms, p < 0.001).
Conclusions: Successful RFCA of slow atrioventricular conduction pathway in patients with AVNRT and AVRT results in improvement of LV systolic and diastolic function. (Cardiol J 2008; 15: 150-155)

Abstract

Background: The impact of radiofrequency current ablation (RFCA) on left ventricular (LV) systolic and diastolic function in patients with atrioventricular nodal re-entrant tachycardia (AVNRT) is not well established yet.
Methods: The study group consisted of 25 patients (18 W, mean age 43 ± 11) with recurrent episodes of AVRT without any concomitant diseases. The control group was formed of 25 healthy volunteers. In both study and control groups, transthorasic echocardiography (TTE) and Doppler were performed in order to assess LV systolic and diastolic function. In AVNRT syndrome patients, TTE was followed by electrophysiology study and RFCA. TTE was repeated after six months in the study group.
Results: Significant differences were found between the study and control groups with regard to LV systolic (FS - fractional shortening: 37 ± 4 vs. 42 ± 6%, p = 0.001; ESV - end-systolic volume: 19 ± 4 vs. 17 ± 4 ml/m2, p = 0.03; EF - ejection fraction: 55 ± 5 vs. 62 ± 4%, p = = 0.001) and diastolic function (E wave: 69 ± 17 vs. 84 ± 15 cm/s, p = 0.002; E/A: 1.09 ± ± 0.42 vs. 1.38 ± 0.27, p = 0.005; DT - duration difference between A and AR waves: 7 ± 29 vs. -28 ± 13 ms, p = 0.001; DT - deceleration time of E wave: 223 ± 34 vs. 177 ± 27 ms, p = 0.001; IVRT - isovolumic relaxation time: 105 ± 15 vs. 86 ± 11 ms, p = 0.001; E/A while Valsalva manoeuvre: 0.93 ± 0.35 vs. 1.25 ± 0.16, p = 0.001; AR - atrial reversal velocity: 27 ± 7 vs. 14 ± 11 cm/s, p = 0.001) variables. In 6-month follow-up decrease in LVESV (19 ± 4 vs. 17 ± 4 ml, p < 0.03) and increase in EF (55 ± 5 vs. 62 ± 4%, p < 0.001) was noted. Doppler analysis showed an increase in E wave (69 ± 17 vs. 79 ± 20 cm/s, p < 0.02), E/A ratio (1.09 ± 0.42 vs. 1.30 ± 0.27, p < 0.006) and decrease in A wave (68 ± 13 vs. 63 ± 10 cm/s, p < 0.02), DT (223 ± 34 vs. 179 ± 22 ms, p < 0.001), IVRT (105 ± 15 vs. 89 ± 11 ms, p < 0.001) and DT (7 ± 29 vs. -13 ± 28 ms, p < 0.001).
Conclusions: Successful RFCA of slow atrioventricular conduction pathway in patients with AVNRT and AVRT results in improvement of LV systolic and diastolic function. (Cardiol J 2008; 15: 150-155)
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Keywords

radiofrequency ablation; re-entrant tachycardia; left ventricular function

About this article
Title

Left ventricular systolic and diastolic function in patients with atrioventricular nodal re-entrant tachycardia treated by radiofrequency current ablation

Journal

Cardiology Journal

Issue

Vol 15, No 2 (2008)

Pages

150-155

Published online

2008-02-21

Bibliographic record

Cardiol J 2008;15(2):150-155.

Keywords

radiofrequency ablation
re-entrant tachycardia
left ventricular function

Authors

Agata Duszańska
Radosław Lenarczyk
Oskar Kowalski
Witold Streb
Ewa Markowicz-Pawlus
Tomasz Kukulski
Zbigniew Kalarus

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