open access

Vol 15, No 5 (2008)
Original articles
Published online: 2008-08-12
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Can prodromal symptoms predict recurrence of vasovagal syncope?

Amir Farjam Fazelifar, Hosein Ali Basiri, Ali Tolooie, Majid Haghjoo, Hamid Barakpour, Zahra Emkanjoo, Hooman Bakhshandeh Abkenar, Mahboubeh Zeighami, Foroozan Asgari, Mohammad Ali Sadr-Ameli
Cardiol J 2008;15(5):446-450.

open access

Vol 15, No 5 (2008)
Original articles
Published online: 2008-08-12

Abstract

Background: Vasovagal syncope (VVS) is a common symptom with empirical therapy and high recurrence rate. Our goal was to determine whether the pattern of presyncopal prodromal symptoms can predict the recurrence probability of vasovagal syncope.
Methods: Seventy-nine consecutive patients (male/female: 53/26) with history of VVS and positive tilt table test (TTT) were enrolled in the study and completed the follow-up time for one year. They all had normal electrocardiograms and cardiac echocardiography without underlying disease. All of them were evaluated meticulously for prodromal symptoms (diaphoresis, nausea, palpitation and blurred vision) and frequency of syncopal spells in their past medical history. They received metoprolol at maximum tolerated dose and were taught tilt training as an empirical therapy after TTT.
Results: Fifty-four patients (68.4%) reported at least one of the four main prodromal symptoms. Median syncopal ± presyncopal spells were 4 episodes. Forty-two patients (53.2%) experienced recurrence of syncope or presyncope during the follow-up period. In recurrent symptomatic patients, diaphoresis had been more significantly reported in their past medical history (p = 0.018) and they had more syncopal spells before TTT (p = 0.001). Age, gender and type of TTT response did not have any effect on the recurrence of VVS.
Conclusions: Patients with a history of diaphoresis as a prodromal symptom and more pretilt syncopal attacks experience more syncopal or presyncopal spells during follow-up.

Abstract

Background: Vasovagal syncope (VVS) is a common symptom with empirical therapy and high recurrence rate. Our goal was to determine whether the pattern of presyncopal prodromal symptoms can predict the recurrence probability of vasovagal syncope.
Methods: Seventy-nine consecutive patients (male/female: 53/26) with history of VVS and positive tilt table test (TTT) were enrolled in the study and completed the follow-up time for one year. They all had normal electrocardiograms and cardiac echocardiography without underlying disease. All of them were evaluated meticulously for prodromal symptoms (diaphoresis, nausea, palpitation and blurred vision) and frequency of syncopal spells in their past medical history. They received metoprolol at maximum tolerated dose and were taught tilt training as an empirical therapy after TTT.
Results: Fifty-four patients (68.4%) reported at least one of the four main prodromal symptoms. Median syncopal ± presyncopal spells were 4 episodes. Forty-two patients (53.2%) experienced recurrence of syncope or presyncope during the follow-up period. In recurrent symptomatic patients, diaphoresis had been more significantly reported in their past medical history (p = 0.018) and they had more syncopal spells before TTT (p = 0.001). Age, gender and type of TTT response did not have any effect on the recurrence of VVS.
Conclusions: Patients with a history of diaphoresis as a prodromal symptom and more pretilt syncopal attacks experience more syncopal or presyncopal spells during follow-up.
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Keywords

vasovagal syncope; prodromal symptoms; beta-blocker therapy

About this article
Title

Can prodromal symptoms predict recurrence of vasovagal syncope?

Journal

Cardiology Journal

Issue

Vol 15, No 5 (2008)

Pages

446-450

Published online

2008-08-12

Bibliographic record

Cardiol J 2008;15(5):446-450.

Keywords

vasovagal syncope
prodromal symptoms
beta-blocker therapy

Authors

Amir Farjam Fazelifar
Hosein Ali Basiri
Ali Tolooie
Majid Haghjoo
Hamid Barakpour
Zahra Emkanjoo
Hooman Bakhshandeh Abkenar
Mahboubeh Zeighami
Foroozan Asgari
Mohammad Ali Sadr-Ameli

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