Vol 16, No 2 (2009)
Review Article
Published online: 2009-01-06
The central nervous system and sudden cardiac death: What should we know?
Cardiol J 2009;16(2):105-112.
Abstract
The role of the central nervous system in the modulation and precipitation of sudden cardiac
death has been a matter of controversy for decades. Establishing a cause-effect relationship in
the setting of a cerebro-vascular event has been complex, as patients with stroke usually have
risk factors for coronary artery disease as well. This article will review both experimental and
clinical evidence relating to the mechanisms that link the central nervous system and the
cardiovascular system. Cardiovascular consequences of stroke and epilepsy will be also reviewed.
Keywords: central nervous systemautonomic nervous systemsudden deathSUDEP