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Reversible changes of electrocardiographic abnormalities after parathyroidectomy in patients with primary hyperparathyroidism
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Abstract
Methods: We studied 57 consecutive patients with primary hyperparathyroidism surgically treated. Electrocardiogram, serum electrolytes, parathyroid hormone, creatinine and albumin measures were obtained before and after surgery and were compared.
Results: The most common basal electrocardiographic abnormalities were left ventricular hypertrophy (LVH, 24.6%), conduction disturbances (16.3%), and short QT and QTc intervals. After surgery, a QTc interval lengthening and a tendency of T wave shortening were observed, as well as an inverse association between QTc interval and serum levels of magnesium and corrected calcium. There were no differences in LVH and conduction disturbances after surgery.
Conclusions: Primary hyperparathyroidism is an important factor in the development of electrocardiographic abnormalities in this population, some of which are not corrected after parathyroidectomy. Further studies are required to demonstrate what factors are associated with persistence of electrocardiographic disturbances after surgery.
Abstract
Methods: We studied 57 consecutive patients with primary hyperparathyroidism surgically treated. Electrocardiogram, serum electrolytes, parathyroid hormone, creatinine and albumin measures were obtained before and after surgery and were compared.
Results: The most common basal electrocardiographic abnormalities were left ventricular hypertrophy (LVH, 24.6%), conduction disturbances (16.3%), and short QT and QTc intervals. After surgery, a QTc interval lengthening and a tendency of T wave shortening were observed, as well as an inverse association between QTc interval and serum levels of magnesium and corrected calcium. There were no differences in LVH and conduction disturbances after surgery.
Conclusions: Primary hyperparathyroidism is an important factor in the development of electrocardiographic abnormalities in this population, some of which are not corrected after parathyroidectomy. Further studies are required to demonstrate what factors are associated with persistence of electrocardiographic disturbances after surgery.
Keywords
electrocardiogram; primary hyperparathyroidism; post parathyroidectomy
About this articleTitle
Reversible changes of electrocardiographic abnormalities after parathyroidectomy in patients with primary hyperparathyroidism
Journal
Issue
Pages
241-245
Published online
2009-03-10
Page views
636
Article views/downloads
3269
DOI
10.5603/cj.21501
Bibliographic record
Cardiol J 2009;16(3):241-245.
Keywords
electrocardiogram
primary hyperparathyroidism
post parathyroidectomy
Authors
Oscar Vázquez-Díaz
Lilia Castillo-Martínez
Arturo Orea-Tejeda
Juan José Orozco-Gutiérrez
Enrique Asensio-Lafuente
Alfredo Reza-Albarrán
Rubén Silva-Tinoco
Verónica Rebollar-González
