Possible role of Helicobacter pylori infection via microvascular dysfunction in cardiac syndrome X

Abstract

Recently, some investigators have reported seeing microvascular dysfunction in patients with cardiac syndrome X (CSX). In addition, Helicobacter pylori (H. pylori), a bacterium causing chronic gastritis and peptic ulcers, has recently been associated with CSX. Yet the mechanism(s) by which H. pylori infection leads to CSX is poorly understood. We propose a link between H. pylori and microvascular dysfunction infection in the development of CSX.