Acute myocardial infarction in a patient with post-splenectomy thrombocytosis: A case report and review of literature

Samad Ghaffari; Leili Pourafkari

doi:10.5603/cj.21423

Vol 17, No 1 (2010)

Case Reports

Submitted: 2013-01-14

Published online: 2010-01-26

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Acute myocardial infarction in a patient with post-splenectomy thrombocytosis: A case report and review of literature

Samad Ghaffari, Leili Pourafkari

DOI: 10.5603/cj.21423

Cardiol J 2010;17(1):79-82.

Vol 17, No 1 (2010)

Case Reports

Submitted: 2013-01-14

Published online: 2010-01-26

Abstract

Unlike essential thrombocytosis, which is associated with thrombotic and hemorrhagic complications, reactive thrombocytosis (RT) is usually considered a benign process without thrombotic complications.
We describe a case of acute myocardial infarction in a young heavy smoker with RT following splenectomy. Coronary angiography showed a linear filling defect at mid-part of left anterior descending artery. We performed balloon angioplasty and stenting for this lesion. Aspirin and clopidogrel were administered. His in-hospital course was uneventful and platelet count returned to the normal range at four month follow-up. We concluded that RT may not be an entirely benign process, especially in patients with a history of smoking. Regular monitoring of platelet count, and possibly antithrombotic agents like aspirin prescription for high risk patients with moderate thrombocytosis, may be useful.
(Cardiol J 2010; 17, 1: 79-82)