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Influence of exercise training on left ventricular diastolic function and its relationship to exercise capacity in patients after myocardial infarction
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Abstract
Methods: Forty-eight males, aged 56.4 ± 7.2 years, with preserved left ventricular systolic function (LVSF) and mild diastolic dysfunction (the ratio of transmitral early left ventricular filling velocity to early diastolic mitral annulus velocity E/E’ > 8 as the average of the septal and lateral annulus velocities), were assigned to either a training group (TG, n = 32) or controls (n = 16). Before, and at the end of the study, all patients underwent a cardiopulmonary test and echocardiography with tissue Doppler imaging (TDI).
Results: After a 4.5-month training program, maximal oxygen consumption increased significantly in TG (26.66 ± 3.88 vs. 28.79 ± 5.00 mL/kg/min, p < 0.0001). TDI-derived E/E’ did not change after the training program. After dividing TG according to septal E/E’s > 10 and < 10 and lateral E/E’l > 8 and < 8, exercise capacity improved significantly only in patients with E/E’s < 10 and E/E’l < 8.
Conclusions: A 4.5-month training program in post-myocardial infarction patients with preserved LVSF and mild diastolic dysfunction led to improved exercise capacity only in TG. The diastolic function did not change significantly. The improvement in exercise capacity was significantly greater in patients with a better LVDF measured by TDI.
(Cardiol J 2010; 17, 2: 136-142)
Abstract
Methods: Forty-eight males, aged 56.4 ± 7.2 years, with preserved left ventricular systolic function (LVSF) and mild diastolic dysfunction (the ratio of transmitral early left ventricular filling velocity to early diastolic mitral annulus velocity E/E’ > 8 as the average of the septal and lateral annulus velocities), were assigned to either a training group (TG, n = 32) or controls (n = 16). Before, and at the end of the study, all patients underwent a cardiopulmonary test and echocardiography with tissue Doppler imaging (TDI).
Results: After a 4.5-month training program, maximal oxygen consumption increased significantly in TG (26.66 ± 3.88 vs. 28.79 ± 5.00 mL/kg/min, p < 0.0001). TDI-derived E/E’ did not change after the training program. After dividing TG according to septal E/E’s > 10 and < 10 and lateral E/E’l > 8 and < 8, exercise capacity improved significantly only in patients with E/E’s < 10 and E/E’l < 8.
Conclusions: A 4.5-month training program in post-myocardial infarction patients with preserved LVSF and mild diastolic dysfunction led to improved exercise capacity only in TG. The diastolic function did not change significantly. The improvement in exercise capacity was significantly greater in patients with a better LVDF measured by TDI.
(Cardiol J 2010; 17, 2: 136-142)
Keywords
exercise training; left ventricular diastolic function; tissue Doppler imaging; exercise capacity


Title
Influence of exercise training on left ventricular diastolic function and its relationship to exercise capacity in patients after myocardial infarction
Journal
Issue
Pages
136-142
Published online
2010-03-29
Bibliographic record
Cardiol J 2010;17(2):136-142.
Keywords
exercise training
left ventricular diastolic function
tissue Doppler imaging
exercise capacity
Authors
Iwona Korzeniowska-Kubacka
Maria Bilińska
Ewa Michalak
Beata Kuśmierczyk-Droszcz
Barbara Dobraszkiewicz-Wasilewska
Ryszard Piotrowicz