open access

Vol 17, No 3 (2010)
Original articles
Published online: 2010-05-28
Submitted: 2013-01-14
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Serum testosterone and short-term mortality in men with acute myocardial infarction

Constantin Militaru, Ionut Donoiu, Ovidiu Dracea, Dan-Dominic Ionescu
Cardiol J 2010;17(3):249-253.

open access

Vol 17, No 3 (2010)
Original articles
Published online: 2010-05-28
Submitted: 2013-01-14

Abstract

Background: A significant and independent association between testosterone levels and coronary events in men and women has not been confirmed in large prospective studies, although some reports have shown that endogenous testosterone concentrations in men are inversely related to cardiovascular and general mortality.
Methods: We aimed to assess the relationship between serum testosterone level and short-time (30-day) mortality in men with acute myocardial infarction.
Results: We included 126 consecutive male patients admitted with acute myocardial infarction. The mean age was 62 ± 13 years. We determined, at admission, serum free testosterone (T) level (using a chemoluminiscence assay), high sensitivity C-reactive protein, N-terminal pro-B-type natriuretic peptide, and glycated hemoglobin level. We analyzed the 30-day mortality.
Conclusions: The mean level of serum T was 4.1 ± 2.9 ng/mL. All non-survivors had T level ≤ 3 ng/mL. A low level of T was independently related to total short-term mortality.
(Cardiol J 2010; 17, 3: 249-253)

Abstract

Background: A significant and independent association between testosterone levels and coronary events in men and women has not been confirmed in large prospective studies, although some reports have shown that endogenous testosterone concentrations in men are inversely related to cardiovascular and general mortality.
Methods: We aimed to assess the relationship between serum testosterone level and short-time (30-day) mortality in men with acute myocardial infarction.
Results: We included 126 consecutive male patients admitted with acute myocardial infarction. The mean age was 62 ± 13 years. We determined, at admission, serum free testosterone (T) level (using a chemoluminiscence assay), high sensitivity C-reactive protein, N-terminal pro-B-type natriuretic peptide, and glycated hemoglobin level. We analyzed the 30-day mortality.
Conclusions: The mean level of serum T was 4.1 ± 2.9 ng/mL. All non-survivors had T level ≤ 3 ng/mL. A low level of T was independently related to total short-term mortality.
(Cardiol J 2010; 17, 3: 249-253)
Get Citation

Keywords

testosterone; myocardial infarction; mortality

About this article
Title

Serum testosterone and short-term mortality in men with acute myocardial infarction

Journal

Cardiology Journal

Issue

Vol 17, No 3 (2010)

Pages

249-253

Published online

2010-05-28

Bibliographic record

Cardiol J 2010;17(3):249-253.

Keywords

testosterone
myocardial infarction
mortality

Authors

Constantin Militaru
Ionut Donoiu
Ovidiu Dracea
Dan-Dominic Ionescu

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