Vol 17, No 4 (2010)
Review Article
Published online: 2010-07-27

open access

Page views 629
Article views/downloads 1260
Get Citation

Connect on Social Media

Connect on Social Media

Safety of pharmacotherapy of osteoporosis in cardiology patients

Tomasz Zapolski, Andrzej Wysokiński
Cardiol J 2010;17(4):335-343.


The commonest medical conditions following menopause are osteoporosis and atherosclerotic disease. This review considers the safety of pharmacotherapy of osteoporosis in cardiology patients. Drugs used for osteoporosis treatment may have adverse effects on the cardiovascular system. This article has detailed analysed of current drug classes, such as the bisphosphonates and strontium ranelate, as well as reviewed of the controversy surrounding hormone replacement therapy (HRT) and the selective estrogen receptor modulators (SERMs). Additionally, we discuss the adverse effects on the heart of calcium and drugs influencing calcium metabolism such as vitamin D, parathormone and calcitonin. We look at the interference between osteoporosis treatment and the drugs used for atherosclerosis. Moreover, the side effects on bones of cardiology drugs are analysed. Lastly, the possible advantages of selected drugs used for cardiovascular diseases in terms of osteoporosis prevention are evaluated.
(Cardiol J 2010; 17, 4: 335-343)

Article available in PDF format

View PDF Download PDF file