open access

Vol 17, No 5 (2010)
Original articles
Published online: 2010-09-23
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Influence of exercise training on leptin levels in patients with stable coronary artery disease: A pilot study

Magdalena Kosydar-Piechna, Maria Bilińska, Jadwiga Janas, Ryszard Piotrowicz
Cardiol J 2010;17(5):477-481.

open access

Vol 17, No 5 (2010)
Original articles
Published online: 2010-09-23

Abstract


Background: This study was designed to examine the influence of exercise training on leptin levels in patients with stable coronary artery disease (CAD).
Methods: Sixty-four male patients, mean age 55.6 ± 6.0 years, were randomized either to six weeks of aerobic training, three times a week, at 60–80% of maximal heart rate (training group, Ex, n = 32) or to a control group (n = 32). Exercise stress test was performed and body mass index (BMI), waist-to-hip ratio (WHR), waist circumference and plasma leptin levels were measured at the beginning and end of the study.
Results: Physical capacity increased significantly only in Ex patients (max workload in METs from 7.7 ± 1.4 to 8.2 ± 1.4, p < 0.05). There were no significant differences between initial and final results in either group in terms of BMI, WHR or waist circumference. Although, at the end of the study, leptin levels did not change in Ex patients (6.7 ± 3.2 vs 6.9 ± 3.6 ng/mL, NS), they did increase significantly in the control group (8.0 ± 4.0 vs 9.3 ± 5.2 ng/mL, p < 0.02).
Conclusions: A short period of exercise training in CAD patients improved their physical capacity, but did not influence BMI, WHR and waist circumference. Exercise training prevented an increase in leptin levels during the study period. (Cardiol J 2010; 17, 5: 477-481)

Abstract


Background: This study was designed to examine the influence of exercise training on leptin levels in patients with stable coronary artery disease (CAD).
Methods: Sixty-four male patients, mean age 55.6 ± 6.0 years, were randomized either to six weeks of aerobic training, three times a week, at 60–80% of maximal heart rate (training group, Ex, n = 32) or to a control group (n = 32). Exercise stress test was performed and body mass index (BMI), waist-to-hip ratio (WHR), waist circumference and plasma leptin levels were measured at the beginning and end of the study.
Results: Physical capacity increased significantly only in Ex patients (max workload in METs from 7.7 ± 1.4 to 8.2 ± 1.4, p < 0.05). There were no significant differences between initial and final results in either group in terms of BMI, WHR or waist circumference. Although, at the end of the study, leptin levels did not change in Ex patients (6.7 ± 3.2 vs 6.9 ± 3.6 ng/mL, NS), they did increase significantly in the control group (8.0 ± 4.0 vs 9.3 ± 5.2 ng/mL, p < 0.02).
Conclusions: A short period of exercise training in CAD patients improved their physical capacity, but did not influence BMI, WHR and waist circumference. Exercise training prevented an increase in leptin levels during the study period. (Cardiol J 2010; 17, 5: 477-481)
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Keywords

coronary artery disease; exercise training; leptin levels

About this article
Title

Influence of exercise training on leptin levels in patients with stable coronary artery disease: A pilot study

Journal

Cardiology Journal

Issue

Vol 17, No 5 (2010)

Pages

477-481

Published online

2010-09-23

Bibliographic record

Cardiol J 2010;17(5):477-481.

Keywords

coronary artery disease
exercise training
leptin levels

Authors

Magdalena Kosydar-Piechna
Maria Bilińska
Jadwiga Janas
Ryszard Piotrowicz

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