open access

Vol 18, No 2 (2011)
Original articles
Published online: 2011-03-10
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Interatrial block in patients with obstructive sleep apnea

Adrian Baranchuk, Brendan Parfrey, Leonard Lim, Florence Morriello, Christopher S. Simpson, Wilma M. Hopman, Damian P. Redfearn, Michael Fitzpatrick
Cardiol J 2011;18(2):171-175.

open access

Vol 18, No 2 (2011)
Original articles
Published online: 2011-03-10

Abstract


Background: Obstructive sleep apnea (OSA) is a common disorder that affects 5% of the adult North American population. It is associated with atrial arrhythmias and stroke. The mechanisms of this association remain unclear. The aim to the study was to identify the factors associated with interatrial block (IAB) among patients with OSA.
Methods: Patients referred for polysomnography were studied. Sleep apnea severity (apnea-hypopnea index [AHI]) was measured in each subject. 12-lead ECGs were scanned and amplified (× 10); P-wave duration and dispersion were measured using a semi-automatic caliper. IAB was defined as a P-wave duration ≥ 120 ms.
Results: Data from 180 consecutive patients was examined. Moderate-severe OSA (mean AHI = 56.2 ± 27.9) was present in 144 (OSA group). The remaining 36 had mild or no OSA (mean AHI = 5.6 ± 3.6) and were used as controls. Age distribution between the groups did not differ and there were more males in the OSA group (69.4% vs 47.2%, p = 0.01). Obesity (78.5% vs 39.4%, p < 0.001) and hypertension (51.4% vs 27.8%, p < 0.01) were more prevalent in the OSA group. IAB was more prevalent in patients with moderate-severe OSA (34.7% OSA vs 0% controls, p < 0.001). In linear regression, age and AHI > 30 were independent predictors of maximum P-wave duration (p = 0.001 and p < 0.001, respectively). P-wave dispersion was significantly higher in the severe OSA group (14.6 ± 7.5 for OSA, 8.9 ± 3.1 controls, p < 0.001).
Conclusions: Older age and moderate-severe OSA are predictors of IAB. P-wave dispersion is increased in patients with moderate-severe OSA. This may partly explain the high prevalence of atrial arrhythmias in patients with OSA. (Cardiol J 2011; 18, 2: 171-175)

Abstract


Background: Obstructive sleep apnea (OSA) is a common disorder that affects 5% of the adult North American population. It is associated with atrial arrhythmias and stroke. The mechanisms of this association remain unclear. The aim to the study was to identify the factors associated with interatrial block (IAB) among patients with OSA.
Methods: Patients referred for polysomnography were studied. Sleep apnea severity (apnea-hypopnea index [AHI]) was measured in each subject. 12-lead ECGs were scanned and amplified (× 10); P-wave duration and dispersion were measured using a semi-automatic caliper. IAB was defined as a P-wave duration ≥ 120 ms.
Results: Data from 180 consecutive patients was examined. Moderate-severe OSA (mean AHI = 56.2 ± 27.9) was present in 144 (OSA group). The remaining 36 had mild or no OSA (mean AHI = 5.6 ± 3.6) and were used as controls. Age distribution between the groups did not differ and there were more males in the OSA group (69.4% vs 47.2%, p = 0.01). Obesity (78.5% vs 39.4%, p < 0.001) and hypertension (51.4% vs 27.8%, p < 0.01) were more prevalent in the OSA group. IAB was more prevalent in patients with moderate-severe OSA (34.7% OSA vs 0% controls, p < 0.001). In linear regression, age and AHI > 30 were independent predictors of maximum P-wave duration (p = 0.001 and p < 0.001, respectively). P-wave dispersion was significantly higher in the severe OSA group (14.6 ± 7.5 for OSA, 8.9 ± 3.1 controls, p < 0.001).
Conclusions: Older age and moderate-severe OSA are predictors of IAB. P-wave dispersion is increased in patients with moderate-severe OSA. This may partly explain the high prevalence of atrial arrhythmias in patients with OSA. (Cardiol J 2011; 18, 2: 171-175)
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Keywords

interatrial block; obstructive sleep apnea

About this article
Title

Interatrial block in patients with obstructive sleep apnea

Journal

Cardiology Journal

Issue

Vol 18, No 2 (2011)

Pages

171-175

Published online

2011-03-10

Bibliographic record

Cardiol J 2011;18(2):171-175.

Keywords

interatrial block
obstructive sleep apnea

Authors

Adrian Baranchuk
Brendan Parfrey
Leonard Lim
Florence Morriello
Christopher S. Simpson
Wilma M. Hopman
Damian P. Redfearn
Michael Fitzpatrick

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