Vol 18, No 6 (2011)
Technology Note
Submitted: 2013-01-14
Published online: 2011-11-23
New developments in the treatment of severe drug resistant hypertension
S. Suave Lobodzinski
DOI: 10.5603/cj.21194
·
Cardiol J 2011;18(6):707-711.
Vol 18, No 6 (2011)
Technology notes
Submitted: 2013-01-14
Published online: 2011-11-23
Abstract
The purpose of this paper is to review the state-of-the-art of renal denervation system technology
for treatment of drug resistant hypertension. We describe an investigational device that is
currently tested in an on-going clinical trial. The denervation device uses the RF thermal
ablation catheter attached to the RF generator. The RF catheter is inserted into the renal artery
and positioned in the vicinity of the efferent and afferent parasympathetic innervations. Renal
denervation is a minimally invasive, localized procedure and the procedural and recovery
times are very short. The entire procedure lasts about 40 min. In early clinical trials, the
systolic blood pressure in 87% of patients who underwent the denervation procedure resulted
in an average blood pressure drop of greater than 10 mm Hg. The procedure has no systematic
side effects, and appears to be beneficial in the management of hypertension in patients
refractory to pharmacological therapy. (Cardiol J 2011; 18, 6: 707–711)
Abstract
The purpose of this paper is to review the state-of-the-art of renal denervation system technology
for treatment of drug resistant hypertension. We describe an investigational device that is
currently tested in an on-going clinical trial. The denervation device uses the RF thermal
ablation catheter attached to the RF generator. The RF catheter is inserted into the renal artery
and positioned in the vicinity of the efferent and afferent parasympathetic innervations. Renal
denervation is a minimally invasive, localized procedure and the procedural and recovery
times are very short. The entire procedure lasts about 40 min. In early clinical trials, the
systolic blood pressure in 87% of patients who underwent the denervation procedure resulted
in an average blood pressure drop of greater than 10 mm Hg. The procedure has no systematic
side effects, and appears to be beneficial in the management of hypertension in patients
refractory to pharmacological therapy. (Cardiol J 2011; 18, 6: 707–711)
Keywords
hypertension; renal denervation; RF ablation
Title
New developments in the treatment of severe drug resistant hypertension
Journal
Cardiology Journal
Issue
Vol 18, No 6 (2011)
Article type
Technology Note
Pages
707-711
Published online
2011-11-23
Page views
506
Article views/downloads
2317
DOI
10.5603/cj.21194
Bibliographic record
Cardiol J 2011;18(6):707-711.
Keywords
hypertension
renal denervation
RF ablation
Authors
S. Suave Lobodzinski
About this article