dostęp otwarty
Analysis of the clinical and pathological characteristics of patients with the squamous-cell lung carcinoma including group survival rates and the occurrence of symptoms depending on the extent of the tumor
Afiliacje- Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland, Zabrze
- Department of Pathomorphology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice
- Department of Thoracic Surgery, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice
dostęp otwarty
Streszczenie
Introduction.Non-small-cell lung carcinoma (NSCLC) constitutes 80% of all lung cancer cases, of which 25–30% are squamous-cell carcinoma (SCC). We investigated the impact of comorbidities and other risk factors on the survival of patients with SCC, including the correlation between symptoms and the maximum tumor size.
Materials and methods.The study cohort included 417 patients. The Kaplan-Meier method, the Log-rank test, Gehan’s generalized Wilcoxon test, the Mann-Whitney U test, the t-test and Cox’s model of proportionality of hazards were applied.
Results.The maximum tumor size exhibited a significant correlation with the presence of symptoms such as cough, hemoptysis, and weight loss. Patients who presented with a positive family history of cancer, a prior history of cancer, respiratory diseases, or hypertension experienced a notably reduced survival time.
Conclusions.Patient’s symptoms and their medical history are important in predicting survival.
Streszczenie
Introduction.Non-small-cell lung carcinoma (NSCLC) constitutes 80% of all lung cancer cases, of which 25–30% are squamous-cell carcinoma (SCC). We investigated the impact of comorbidities and other risk factors on the survival of patients with SCC, including the correlation between symptoms and the maximum tumor size.
Materials and methods.The study cohort included 417 patients. The Kaplan-Meier method, the Log-rank test, Gehan’s generalized Wilcoxon test, the Mann-Whitney U test, the t-test and Cox’s model of proportionality of hazards were applied.
Results.The maximum tumor size exhibited a significant correlation with the presence of symptoms such as cough, hemoptysis, and weight loss. Patients who presented with a positive family history of cancer, a prior history of cancer, respiratory diseases, or hypertension experienced a notably reduced survival time.
Conclusions.Patient’s symptoms and their medical history are important in predicting survival.
Słowa kluczowe
lung; carcinoma; squamous-cell; survival analysis
Informacje o artykuleTytuł
Analysis of the clinical and pathological characteristics of patients with the squamous-cell lung carcinoma including group survival rates and the occurrence of symptoms depending on the extent of the tumor
Czasopismo
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory
Numer
Typ artykułu
Praca badawcza (oryginalna)
Strony
420-428
Opublikowany online
2023-12-27
Wyświetlenia strony
245
Wyświetlenia/pobrania artykułu
46
Rekord bibliograficzny
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2023;8(6):420-428.
Słowa kluczowe
lung
carcinoma
squamous-cell
survival analysis
Autorzy
Weronika Targosz
Julia Świerczek
Błażej Ochman
Paweł Kiczmer
Paweł Ziora
Mateusz Rydel
Damian Czyżewski
Maciej Borowiecki
Bogna Drozdowska
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