Tom 7, Nr 2 (2022)
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Opublikowany online: 2022-02-18

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An extrapleural solitary fibrous tumor with low metastatic potential in a young female

Przemysław Jakub Cuber12, Tomasz Wojewoda12, Wojciech M. Wysocki123
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2022;7(2):141.



Obrazy w onkologii / Pictures in oncology

Biuletyn Polskiego
Towarzystwa Onkologicznego

2022, tom 7, nr 2, 141

© Polskie Towarzystwo Onkologiczne

ISSN 2543–5248, e-ISSN: 2543–8077

An extrapleural solitary fibrous tumor with low metastatic potential in a young female

Przemysław J. Cuber12Tomasz Wojewoda12Wojciech M. Wysocki123
1Chair of Surgery, Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland
2Department of General, Oncological and Vascular Surgery, 5th Military Clinical Hospital in Krakow, Krakow, Poland
3Scientific Editorial Office, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland

Jak cytować / How to cite:

Cuber PJ, Wojewoda T, Wysocki WM. An extrapleural solitary fibrous tumor with low metastatic potential in a young female. NOWOTWORY J Oncol 2022; 72: 130.

Solitary fibrous tumors (SFT) for decades were reported only in the pleura (until the 1990s) and were considered a histomorphological entity similar to hemangiopericytoma. Currently both these neoplasms are merged together by the WHO and defined as fibroblastic neoplasms with intermediate behavior, rarely metastasizing [1].

A 25-year-old female with a 5 cm tumor on her thigh, adjacent but superficial to the fascia, with high vasculature as seen on the MRI (fig. 1), underwent a wide local excision for suspected sarcoma. Pathology reported SFT with low metastatic potential as based on the WHO risk criteria (age = 0, mitotic index = 2, tumor size = 0, necrosis = 0; altogether 2 points). Surgery was R0, with the tumor capsule intact (fig. 2). The presence of STAT6 nuclear staining is characteristic for SFT.

Figure 1. In the upper-posterior portion of the thigh, a well-circumscribed 5 cm tumor adjacent to the fascia can be seen
Figure 2. A microscopic image of a solitary fibrous tumor of the thigh (courtesy of Dariusz Pabis, MD)

Thorax (30%), meninges, (27%) and abdomen (20%) are leading locations for SFT; SFT occurs mainly >50 years (40–70). Extra-pleural locations warrant a careful pathological work-out to rule out other more frequent soft tissue tumors. A recurrence of any SFT variant is always possible, with a risk
of de-differentiation [2].


  1. Tariq MU, Din NUd, Abdul-Ghafar J, et al. The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior. Diagn Pathol. 2021; 16(1): 32, doi: 10.1186/s13000-021-01095-2, indexed in Pubmed: 33879215.
  2. Martin-Broto J, Mondaza-Hernandez JL, Moura DS, et al. A Comprehensive Review on Solitary Fibrous Tumor: New Insights for New Horizons. Cancers (Basel). 2021; 13(12), doi: 10.3390/cancers13122913, indexed in Pubmed: 34200924.

Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory