Tom 6, Nr 6 (2021)
Artykuł przeglądowy
Opublikowany online: 2021-12-07

dostęp otwarty

Wyświetlenia strony 3475
Wyświetlenia/pobrania artykułu 3911
Pobierz cytowanie

Eksport do Mediów Społecznościowych

Eksport do Mediów Społecznościowych

Ryzyko powikłań po mastektomii, rekonstrukcji piersi i radioterapii w zależności od techniki rekonstrukcyjnej

Anna Niwińska1
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2021;6(6):466-474.

Streszczenie

Postępy w technikach rekonstrukcyjnych obserwowane w ostatnich latach zmieniły standardy postępowania z chorymi na raka piersi. Obecnie, każda chora w I, II i III stopniu klinicznego zaawansowania, z wyjątkiem zapalnego raka piersi, ma możliwość odtworzenia piersi. Radioterapia zwiększa ryzyko powikłań po zabiegach rekonstrukcyjnych. Dokonano przeglądu piśmiennictwa dotyczącego typów rekonstrukcji piersi i radioterapii w aspekcie ryzyka powikłań, aby wyselekcjonować najbezpieczniejszą metodę odtwórczą piersi. Wyniki wskazują na rekonstrukcję natychmiastową z tkanek własnych jako najmniej obciążoną powikłaniami u pacjentek napromienianych. Codzienna praktyka kliniczna potwierdza jednak różno­rodność stosowanych metod rekonstrukcji z radioterapią, gdyż – poza udokumentowanymi działaniami niepożądanymi – każda z metod rekonstrukcyjnych ma swoje zalety i wady.

Artykuł dostępny w formacie PDF

Pokaż PDF Pobierz plik PDF

Referencje

  1. Sekiguchi K, Kawamori J, Yamauchi H. Breast reconstruction and postmastectomy radiotherapy: complications by type and timing and other problems in radiation oncology. Breast Cancer. 2017; 24(4): 511–520.
  2. Cardoso F, Kyriakides S, Ohno S, et al. ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†. Ann Oncol. 2019; 30(8): 1194–1220.
  3. Burstein HJ, Curigliano G, Loibl S, et al. Members of the St. Gallen International Consensus Panel on the Primary Therapy of Early Breast Cancer 2019. Estimating the benefits of therapy for early-stage breast cancer: the St. Gallen International Consensus Guidelines for the primary therapy of early breast cancer 2019. Ann Oncol. 2019; 30(10): 1541–1557.
  4. Jassem J, Krzakowski M, Bobek-Billewicz B, et al. Breast cancer. Oncol Clin Pract. 2020; 16(5): 207–260.
  5. Kappos EA, Weber WP, de Boniface J, et al. Immediate Breast Reconstruction. Breast Care (Basel). 2020; 15(2): 188–191.
  6. Wagner RD, Braun TL, Zhu H, et al. A systematic review of complications in prepectoral breast reconstruction. J Plast Reconstr Aesthet Surg. 2019; 72(7): 1051–1059.
  7. Vidya R, Berna G, Sbitany H, et al. Prepectoral implant-based breast reconstruction: a joint consensus guide from UK, European and USA breast and plastic reconstructive surgeons. Ecancermedicalscience. 2019; 13: 927.
  8. Sbitany H, Gomez-Sanchez C, Piper M, et al. Prepectoral Breast Reconstruction in the Setting of Postmastectomy Radiation Therapy: An Assessment of Clinical Outcomes and Benefits. Plast Reconstr Surg. 2019; 143(1): 10–20.
  9. Seth AK, Hirsch EM, Fine NA, et al. Utility of acellular dermis-assisted breast reconstruction in the setting of radiation: a comparative analysis. Plast Reconstr Surg. 2012; 130(4): 750–758.
  10. Sinnott CJ, Persing SM, Pronovost M, et al. Impact of Postmastectomy Radiation Therapy in Prepectoral Versus Subpectoral Implant-Based Breast Reconstruction. Ann Surg Oncol. 2018; 25(10): 2899–2908.
  11. Thuman JM, Worbowtiz N, Jain A, et al. Impact of Radiation on Implant-Based Breast Reconstruction in Prepectoral Versus Submuscular Planes. Ann Plast Surg. 2021; 86(6S Suppl 5): S560–S566.
  12. Yun JH, Diaz R, Orman AG. Breast Reconstruction and Radiation Therapy. Cancer Control. 2018; 25(1): 1073274818795489.
  13. Wilkins EG, Hamill JB, Kim HM, et al. Complications in Postmastectomy Breast Reconstruction: One-year Outcomes of the Mastectomy Reconstruction Outcomes Consortium (MROC) Study. Ann Surg. 2018; 267(1): 164–170.
  14. Cooke AL, Diaz-Abele J, Hayakawa T, et al. Radiation Therapy Versus No Radiation Therapy to the Neo-breast Following Skin-Sparing Mastectomy and Immediate Autologous Free Flap Reconstruction for Breast Cancer: Patient-Reported and Surgical Outcomes at 1 Year-A Mastectomy Reconstruction Outcomes Consortium (MROC) Substudy. Int J Radiat Oncol Biol Phys. 2017; 99(1): 165–172.
  15. Kaidar-Person O, Hermann N, Poortmans P, et al. A multidisciplinary approach for autologous breast reconstruction: A narrative (re)view for better management. Radiother Oncol. 2021; 157: 263–271.
  16. Towpik E. Postmastectomy breast reconstruction: 15 years of experiences of the warsaw cancer Center. Nowotwory Journal Of Oncology. 2000; 50(5): 529–535.
  17. Mazur S, Nagadowska M, Chmielewski R, et al. Postoperative complications and risk of recurrence after skin sparing mastectomy and immediate reconstruction with autologous tissues: 9-year experience. Nowotwory Journal of Oncology. 2009; 59(6): 436–441.
  18. Maciejewski A, Dobrut M, Szumniak R, et al. The use of perforator free flaps (DIEP, SGAP) in bilateral breast reconstruction after different types of mastectomy. Cases presentation. Nowotwory Journal of Oncology. 2009; 59(4): 274–279.
  19. Meattini I, Becherini C, Bernini M, et al. Breast reconstruction and radiation therapy: An Italian expert Delphi consensus statements and critical review. Cancer Treat Rev. 2021; 99: 102236.
  20. Chen JJ, von Eyben R, Gutkin PM, et al. Development of a Classification Tree to Predict Implant-Based Reconstruction Failure with or without Postmastectomy Radiation Therapy for Breast Cancer. Ann Surg Oncol. 2021; 28(3): 1669–1679.
  21. Muresan H, Lam G, Cooper BT, et al. Impact of Evolving Radiation Therapy Techniques on Implant-Based Breast Reconstruction. Plast Reconstr Surg. 2017; 139(6): 1232e–1239e.
  22. Anker CJ, Hymas RV, Ahluwalia R, et al. The Effect of Radiation on Complication Rates and Patient Satisfaction in Breast Reconstruction using Temporary Tissue Expanders and Permanent Implants. Breast J. 2015; 21(3): 233–240.
  23. Ricci JA, Epstein S, Momoh AO, et al. A meta-analysis of implant-based breast reconstruction and timing of adjuvant radiation therapy. J Surg Res. 2017; 218: 108–116.
  24. Fowble B, Park C, Wang F, et al. Rates of Reconstruction Failure in Patients Undergoing Immediate Reconstruction With Tissue Expanders and/or Implants and Postmastectomy Radiation Therapy. Int J Radiat Oncol Biol Phys. 2015; 92(3): 634–641.
  25. Nahabedian MY, Tsangaris T, Momen B, et al. Infectious complications following breast reconstruction with expanders and implants. Plast Reconstr Surg. 2003; 112(2): 467–476.
  26. Christante D, Pommier SJ, Diggs BS, et al. Using complications associated with postmastectomy radiation and immediate breast reconstruction to improve surgical decision making. Arch Surg. 2010; 145(9): 873–878.
  27. Chang DW, Barnea Y, Robb GL. Effects of an autologous flap combined with an implant for breast reconstruction: an evaluation of 1000 consecutive reconstructions of previously irradiated breasts. Plast Reconstr Surg. 2008; 122(2): 356–362.
  28. Ascherman JA, Hanasono MM, Newman MI, et al. Implant reconstruction in breast cancer patients treated with radiation therapy. Plast Reconstr Surg. 2006; 117(2): 359–365.
  29. Vieira RA, Ribeiro LM, Carrara GF, et al. Effectiveness and Safety of Implant-Based Breast Reconstruction in Locally Advanced Breast Carcinoma: A Matched Case-Control Study. Breast Care (Basel). 2019; 14(4): 200–210.
  30. Billig J, Jagsi R, Qi Ji, et al. Should Immediate Autologous Breast Reconstruction Be Considered in Women Who Require Postmastectomy Radiation Therapy? A Prospective Analysis of Outcomes. Plast Reconstr Surg. 2017; 139(6): 1279–1288.
  31. Rochlin DH, Jeong AR, Goldberg L, et al. Postmastectomy radiation therapy and immediate autologous breast reconstruction: integrating perspectives from surgical oncology, radiation oncology, and plastic and reconstructive surgery. J Surg Oncol. 2015; 111(3): 251–257.
  32. Spear SL, Ducic I, Low M, et al. The effect of radiation on pedicled TRAM flap breast reconstruction: outcomes and implications. Plast Reconstr Surg. 2005; 115(1): 84–95.
  33. Kelley BP, Ahmed R, Kidwell KM, et al. A systematic review of morbidity associated with autologous breast reconstruction before and after exposure to radiotherapy: are current practices ideal? Ann Surg Oncol. 2014; 21(5): 1732–1738.
  34. Spear SL, Onyewu C. Staged breast reconstruction with saline-filled implants in the irradiated breast: recent trends and therapeutic implications. Plast Reconstr Surg. 2000; 105(3): 930–942.
  35. Nava MB, Pennati AE, Lozza L, et al. Outcome of different timings of radiotherapy in implant-based breast reconstructions. Plast Reconstr Surg. 2011; 128(2): 353–359.
  36. Cordeiro PG, Albornoz CR, McCormick B, et al. What Is the Optimum Timing of Postmastectomy Radiotherapy in Two-Stage Prosthetic Reconstruction: Radiation to the Tissue Expander or Permanent Implant? Plast Reconstr Surg. 2015; 135(6): 1509–1517.
  37. Ho AL, Bovill ES, Macadam SA, et al. Postmastectomy radiation therapy after immediate two-stage tissue expander/implant breast reconstruction: a University of British Columbia perspective. Plast Reconstr Surg. 2014; 134(1): 1e–110e.
  38. Anderson PR, Freedman G, Nicolaou N, et al. Postmastectomy chest wall radiation to a temporary tissue expander or permanent breast implant--is there a difference in complication rates? Int J Radiat Oncol Biol Phys. 2009; 74(1): 81–85.
  39. Pu Y, Mao TC, Zhang YM, et al. The role of postmastectomy radiation therapy in patients with immediate prosthetic breast reconstruction: A meta-analysis. Medicine (Baltimore). 2018; 97(6): e9548.
  40. Hong WJ, Zhang GY, Chen CL, et al. The Effect of Previous Irradiation for Patients With Prosthetic Breast Reconstruction: A Meta-Analysis. Aesthet Surg J. 2021; 41(7): NP748–NP757.
  41. Li L, Su Y, Xiu B, et al. Comparison of prepectoral and subpectoral breast reconstruction after mastectomies: A systematic review and meta analysis. Eur J Surg Oncol. 2019; 45(9): 1542–1550.
  42. Abbate O, Rosado N, Sobti N, et al. Meta-analysis of prepectoral implant-based breast reconstruction: guide to patient selection and current outcomes. Breast Cancer Res Treat. 2020; 182(3): 543–554.
  43. Nahabedian MY, Cocilovo C. Two-Stage Prosthetic Breast Reconstruction: A Comparison Between Prepectoral and Partial Subpectoral Techniques. Plast Reconstr Surg. 2017; 140(6S Prepectoral Breast Reconstruction): 22S–30S.
  44. Patel AA, Arquette CP, Yesantharao PS, et al. Examining the Effects of Postmastectomy Radiation Therapy in Prepectoral Versus Subpectoral Autologous Breast Reconstruction. Ann Plast Surg. 2021; 86(5S Suppl 3): S390–S394.
  45. Dave RV, Vucicevic A, Barrett E, et al. Risk factors for complications and implant loss after prepectoral implant-based immediate breast reconstruction: medium-term outcomes in a prospective cohort. Br J Surg. 2021; 108(5): 534–541.
  46. Chung SY, Chang JS, Shin KH, et al. Impact of radiation dose on complications among women with breast cancer who underwent breast reconstruction and post-mastectomy radiotherapy: A multi-institutional validation study. Breast. 2021; 56: 7–13.
  47. Barry M, Kell MR. Radiotherapy and breast reconstruction: a meta-analysis. Breast Cancer Res Treat. 2011; 127(1): 15–22.
  48. O'Donnell JPM, Murphy D, Ryan ÉJ, et al. Optimal reconstructive strategies in the setting of post-mastectomy radiotherapy - A systematic review and network meta-analysis. Eur J Surg Oncol. 2021 [Epub ahead of print].
  49. Huang Y, Sanz J, Rodríguez N, et al. Effects of radiation on toxicity, complications, revision surgery and aesthetic outcomes in breast reconstruction: An argument about timing and techniques. J Plast Reconstr Aesthet Surg. 2021 [Epub ahead of print].
  50. Kim DY, Park E, Heo CY, et al. Hypofractionated versus conventional fractionated radiotherapy for breast cancer in patients with reconstructed breast: Toxicity analysis. Breast. 2021; 55: 37–44.
  51. Tanos G, Prousskaia E, Chow W, et al. Locally Advanced Breast Cancer: Autologous Versus Implant-based Reconstruction. Plast Reconstr Surg Glob Open. 2016; 4(2): e622.
  52. Chetta MD, Aliu O, Zhong L, et al. Reconstruction of the Irradiated Breast: A National Claims-Based Assessment of Postoperative Morbidity. Plast Reconstr Surg. 2017; 139(4): 783–792.
  53. Jagsi R, Momoh AO, Qi Ji, et al. Impact of Radiotherapy on Complications and Patient-Reported Outcomes After Breast Reconstruction. J Natl Cancer Inst. 2018; 110(2).
  54. Manyam BV, Shah C, Woody NM, et al. Long-Term Outcomes After Autologous or Tissue Expander/Implant-Based Breast Reconstruction and Postmastectomy Radiation for Breast Cancer. Pract Radiat Oncol. 2019; 9(6): e497–e505.
  55. Reinders FCJ, Young-Afat DA, Batenburg MCT, et al. Higher reconstruction failure and less patient-reported satisfaction after post mastectomy radiotherapy with immediate implant-based breast reconstruction compared to immediate autologous breast reconstruction. Breast Cancer. 2020; 27(3): 435–444.
  56. Naoum GE, Salama L, Niemierko A, et al. Single Stage Direct-to-Implant Breast Reconstruction Has Lower Complication Rates Than Tissue Expander and Implant and Comparable Rates to Autologous Reconstruction in Patients Receiving Postmastectomy Radiation. Int J Radiat Oncol Biol Phys. 2020; 106(3): 514–524.
  57. Hershenhouse KS, Bick K, Shauly O, et al. "Systematic review and meta-analysis of immediate versus delayed autologous breast reconstruction in the setting of post-mastectomy adjuvant radiation therapy". J Plast Reconstr Aesthet Surg. 2021; 74(5): 931–944.
  58. Heiman AJ, Gabbireddy SR, Kotamarti VS, et al. A Meta-Analysis of Autologous Microsurgical Breast Reconstruction and Timing of Adjuvant Radiation Therapy. J Reconstr Microsurg. 2021; 37(4): 336–345.
  59. Santosa KB, Qi Ji, Kim HM, et al. Long-term Patient-Reported Outcomes in Postmastectomy Breast Reconstruction. JAMA Surg. 2018; 153(10): 891–899.
  60. Miseré RMl, van Kuijk SMj, Claassens EL, et al. Breast-related and body-related quality of life following autologous breast reconstruction is superior to implant-based breast reconstruction - A long-term follow-up study. Breast. 2021; 59: 176–182.
  61. Nelson JA, Allen RJ, Polanco T, et al. Long-term Patient-reported Outcomes Following Postmastectomy Breast Reconstruction: An 8-year Examination of 3268 Patients. Ann Surg. 2019; 270(3): 473–483.
  62. Toyserkani NM, Jørgensen MG, Tabatabaeifar S, et al. Autologous versus implant-based breast reconstruction: A systematic review and meta-analysis of Breast-Q patient-reported outcomes. J Plast Reconstr Aesthet Surg. 2020; 73(2): 278–285.
  63. Craig ES, Lentz R, Srinivasa D, et al. Three-dimensional Analysis of How Radiation Affects Deep Inferior Epigastric Perforator (DIEP) Flap Volume, Projection, and Position in Breast Cancer Reconstruction. Ann Plast Surg. 2018; 81(2): 235–239.
  64. Weber WP, Morrow M, Boniface Jde, et al. Oncoplastic Breast Consortium. Knowledge gaps in oncoplastic breast surgery. Lancet Oncol. 2020; 21(8): e375–e385.
  65. Kaidar-Person O, Offersen BV, Boersma LJ, et al. A multidisciplinary view of mastectomy and breast reconstruction: Understanding the challenges. Breast. 2021; 56: 42–52.