Tom 6, Nr 4 (2021)
Krótkie doniesienie naukowe
Opublikowany online: 2021-08-19

dostęp otwarty

Wyświetlenia strony 146
Wyświetlenia/pobrania artykułu 111
Pobierz cytowanie

Eksport do Mediów Społecznościowych

Eksport do Mediów Społecznościowych

Lung volume irradiation procedures in patients with pneumonia during COVID-19 infection – physical aspects of treatment planning and dosimetry

Krzysztof Ślosarek1, Adam Gądek1, Łukasz Sroka1, Łukasz Dolla1, Andrzej Biały1, Michał Radwan1, Dawid Bodusz2, Michał Nachlik2, Tomasz Rutkowski3, Jerzy Jaroszewicz4
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2021;6(4):302-306.

Streszczenie

Introduction. The paper presents an original, used in our Institute, method of lung volume irradiation in patients with pneumonia during COVID-19 infection.

Material and methods. Procedures such as the simulation of treatment and radiotherapy are performed in a treatment room. Real time radiation treatment planning is realized as 2D planning (Irreg Planning VMS) in a separate room, and the 3D (eclipse VMS) dose distribution is calculated after the treatment. During radiation exposure, a fluence map is measured.

Results. A method of irradiating the lungs of patients with COVID-19 was developed, which allows to shorten the time the patient is on the treatment table and minimize contacts between the patient and staff.

Conclusions. The presented procedure made it possible to minimize the time of patient’s stay in the radiotherapy department and at the same time, it retains all the required quality assurance procedures in radiotherapy treatment.

Artykuł dostępny w formacie PDF

Pokaż PDF (angielski) Pobierz plik PDF

Referencje

  1. ECalabrese EJ, Dhawan G. How Radiotherapy Was Historically Used To Treat Pneumonia: Could It Be Useful today ? Yale Journal Of Biology And medicine. 2013; 86: 555–570i.
  2. Park SH, Lee J. Radiotherapy, a New Treatment Option for Non-malignant Disorders: Radiobiological Mechanisms, Clinical Applications, and Radiation Risk. Journal of Rheumatic Diseases. 2017; 24(2): 74.
  3. Musser JH. A study of metabolism in leukaemia, under the influence of the x-ray. TraAm Physician. 1905; 20: 294–323.
  4. Arenas M, Gil F, Gironella M, et al. Anti-inflammatory effects of low-dose radiotherapy in an experimental model of systemic inflammation in mice. Int J Radiat Oncol Biol Phys. 2006; 66(2): 560–567.
  5. Torres Royo L, Antelo Redondo G, Árquez Pianetta M, et al. Low-Dose radiation therapy for benign pathologies. Rep Pract Oncol Radiother. 2020; 25(2): 250–254.
  6. Moldeveanu B, Otmishi P, Jani P, et al. Inflammatory mechanisms in the lung. Journal of Inflammation Reaserch. 2009: 1–11.
  7. Schröder S, Kriesen S, Paape D, et al. Modulation of Inflammatory Reactions by Low-Dose Ionizing Radiation: Cytokine Release of Murine Endothelial Cells Is Dependent on Culture Conditions. J Immunol Res. 2018; 2018: 2856518.
  8. Ameri A, Rahnama N, Bozorgmehr R, et al. Low-Dose Whole-Lung Irradiation for COVID-19 Pneumonia: Short Course Results. Int J Radiat Oncol Biol Phys. 2020; 108(5): 1134–1139.
  9. Kirkby C, Mackenzie M. Is low dose radiation therapy a potential treatment for COVID-19 pneumonia? Radiother Oncol. 2020; 147: 221.
  10. Taghizadeh-Hesary F, Akbari H. The powerful immune system against powerful COVID-19: A hypothesis. Med Hypotheses. 2020; 140: 109762.
  11. ECLIPSE Photon and Electron Algorithms Reference Guide, P1020505-003-C, Varian Medical Systems. Acesso em: July 2018.



Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory