dostęp otwarty
Survival analysis of patients with locally advanced non-small cell lung cancer treated at the Nu-Med Radiotherapy Center in Elbląg
, 2, 3, 1, 1, 4
Afiliacje- Nu-Med Radiotherapy Center, Elblag
- Department of Psychology and Sociology of Health and Public Health, School of Public Health, University of Warmia and Mazury in Olsztyn Department of Public Health, Medical University of Warsaw
- Department of Oncology, Faculty of Medical Sciences, Collegium Medicum, University of Warmia and Mazury in Olsztyn
- Department of Oncology and Radiotherapy, Medical University of Gdansk
dostęp otwarty
Streszczenie
Introduction. The study aimed to report the efficiency of radical radiotherapy and chemoradiotherapy in patients with non-small cell lung cancer (NSCLC) treated in the Nu-Med Radiotherapy Center in Elbląg.
Material and methods. Ninety-two patients diagnosed with NSCLC treated between 2013 and 2016 were included in the analysis. Overall survival (OS) was estimated by the Kaplan-Meier method.
Results. The 2-year OS for all patients was 36% (median 1.5 years). Two prognostic factors had a significant impact: treatment method and performance status (PS). Patients who underwent concurrent radiochemotherapy and were treated sequentially had a better 2-year OS in comparison with those treated with radiotherapy alone (respectively 46% and 37% vs. 25%, p ≤ 0.05). Patients with PS 0–1 had better OS (median 1.6 years) compared with PS 2 (median 0.7 years, p = 0.04). Other prognostic factors analysed had no impact on OS in our study.
Conclusions. The treatment results of our patients are comparable to those in published trials and meta-analyses.
Streszczenie
Introduction. The study aimed to report the efficiency of radical radiotherapy and chemoradiotherapy in patients with non-small cell lung cancer (NSCLC) treated in the Nu-Med Radiotherapy Center in Elbląg.
Material and methods. Ninety-two patients diagnosed with NSCLC treated between 2013 and 2016 were included in the analysis. Overall survival (OS) was estimated by the Kaplan-Meier method.
Results. The 2-year OS for all patients was 36% (median 1.5 years). Two prognostic factors had a significant impact: treatment method and performance status (PS). Patients who underwent concurrent radiochemotherapy and were treated sequentially had a better 2-year OS in comparison with those treated with radiotherapy alone (respectively 46% and 37% vs. 25%, p ≤ 0.05). Patients with PS 0–1 had better OS (median 1.6 years) compared with PS 2 (median 0.7 years, p = 0.04). Other prognostic factors analysed had no impact on OS in our study.
Conclusions. The treatment results of our patients are comparable to those in published trials and meta-analyses.
Słowa kluczowe
non-small cell lung cancer; chemoradiotherapy; radiotherapy; overall survival
Informacje o artykuleTytuł
Survival analysis of patients with locally advanced non-small cell lung cancer treated at the Nu-Med Radiotherapy Center in Elbląg
Czasopismo
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory
Numer
Strony
184-192
Opublikowany online
2020-07-28
Wyświetlenia strony
218
Wyświetlenia/pobrania artykułu
122
Rekord bibliograficzny
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2020;5(4):184-192.
Słowa kluczowe
non-small cell lung cancer
chemoradiotherapy
radiotherapy
overall survival
Autorzy
Marcin Kurowicki
Karolina Osowiecka
Sergiusz Nawrocki
Łukasz Cieśliński
Barbara Szostakiewicz
Andrzej Badzio
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