dostęp otwarty
Surgical treatment of metastatic gallbladder cancer. Systematic review with own experience
dostęp otwarty
Streszczenie
Introduction. Patients with metastatic gallbladder cancer (GBC) are generally considered incurable and compelled to palliative chemotherapy. Nevertheless, there are numerous reports of successful surgical management of metastatic GBC. The impact of such treatment is yet unclear. Material and methods. We conducted a systematic literature review within Medline and Scopus databases using the following pattern: “gallbladder” and “cancer” and “dissemination”. Also, our own experience with two resected metastatic GBC patients was added to the results. Discussion. The literature search yielded 8 publications with a total of hundred and twelve patients fulfilling the inclusion criteria. Two additional patients were included in the analysis: one with resected GBC liver metastasis and the second with resected GBC diaphragmatic metastasis. A total of hundred and fourteen patients who underwent resection of a solid organ GBC metastasis were analyzed. The study confirmed a rare long-term survival after resection of an isolated GBC metastasis. Conclusions. There is no clear indication for surgical management of gallbladder cancer metastasis. In selected cases, an aggressive surgical approach may be justified.
Streszczenie
Introduction. Patients with metastatic gallbladder cancer (GBC) are generally considered incurable and compelled to palliative chemotherapy. Nevertheless, there are numerous reports of successful surgical management of metastatic GBC. The impact of such treatment is yet unclear. Material and methods. We conducted a systematic literature review within Medline and Scopus databases using the following pattern: “gallbladder” and “cancer” and “dissemination”. Also, our own experience with two resected metastatic GBC patients was added to the results. Discussion. The literature search yielded 8 publications with a total of hundred and twelve patients fulfilling the inclusion criteria. Two additional patients were included in the analysis: one with resected GBC liver metastasis and the second with resected GBC diaphragmatic metastasis. A total of hundred and fourteen patients who underwent resection of a solid organ GBC metastasis were analyzed. The study confirmed a rare long-term survival after resection of an isolated GBC metastasis. Conclusions. There is no clear indication for surgical management of gallbladder cancer metastasis. In selected cases, an aggressive surgical approach may be justified.
Słowa kluczowe
gallbladder cancer, metastatic disease, surgery
Informacje o artykuleTytuł
Surgical treatment of metastatic gallbladder cancer. Systematic review with own experience
Czasopismo
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory
Numer
Strony
57-60
Opublikowany online
2019-08-09
Wyświetlenia strony
238
Wyświetlenia/pobrania artykułu
335
Rekord bibliograficzny
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2019;4(2):57-60.
Słowa kluczowe
gallbladder cancer
metastatic disease
surgery
Autorzy
Oleksandr Legkiy
Dagmara Kozłowska
Jacek Mazur
Andrzej L. Komorowski
