dostęp otwarty
Insights into etiological factors of pulmonary hypertension in cancer patients
Afiliacje- Medical Oncology and Clinical Trials Department, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia
dostęp otwarty
Streszczenie
Pulmonary hypertension is a rare vascular disease that can affect patients with or surviving malignancy resulting in significant morbidity and high mortality. Malignant diseases can lead to elevated pulmonary artery pressure through different mechanisms, either directly by structural obstruction of pulmonary vessels or indirectly through hypercoagulable state or treatment toxicity culminating in high pulmonary vascular resistance. The most common causes of cancer-related pulmonary hypertension are thromboembolic diseases, tumour emboli and treatment toxicity and less commonly intravascular tumours and malignant extrinsic compression.
Streszczenie
Pulmonary hypertension is a rare vascular disease that can affect patients with or surviving malignancy resulting in significant morbidity and high mortality. Malignant diseases can lead to elevated pulmonary artery pressure through different mechanisms, either directly by structural obstruction of pulmonary vessels or indirectly through hypercoagulable state or treatment toxicity culminating in high pulmonary vascular resistance. The most common causes of cancer-related pulmonary hypertension are thromboembolic diseases, tumour emboli and treatment toxicity and less commonly intravascular tumours and malignant extrinsic compression.
Słowa kluczowe
pulmonary hypertension, pulmonary arterial hypertension, pulmonary veno-occlusive disease, cancer, chemotherapy, cardiac toxicity
Informacje o artykuleTytuł
Insights into etiological factors of pulmonary hypertension in cancer patients
Czasopismo
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory
Numer
Strony
306-312
Opublikowany online
2018-01-19
Wyświetlenia strony
325
Wyświetlenia/pobrania artykułu
506
Rekord bibliograficzny
Biuletyn Polskiego Towarzystwa Onkologicznego Nowotwory 2017;2(4):306-312.
Słowa kluczowe
pulmonary hypertension
pulmonary arterial hypertension
pulmonary veno-occlusive disease
cancer
chemotherapy
cardiac toxicity
Autorzy
Loma Al-Mansouri
Firas Al-Obaidi
