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Advances in Palliative Medicine
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open access

Vol 11, No 2 (2012)
Review articles
Published online: 2013-03-15
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The systemic effects of local infiltrations with corticosteroids. Implications for palliative care?

Zbigniew Zylicz
Advances in Palliative Medicine 2012;11(2):74-77.

open access

Vol 11, No 2 (2012)
Review articles
Published online: 2013-03-15

Abstract

Corticosteroids are used in approximately 50% of palliative care patients. Increasingly corticosteroids are used as local infiltrations together with local anaesthetics. This treatment may be adjuvant to other measures to control pain. Depo preparations, although their main activity is topical, may also exercise systemic toxicity. This may include transient suppression of adrenal activity which may be exacerbated by the use of morphine. Some women in reproductive age may experience vaginal blood loss between the periods. Other toxicities are rare.

Abstract

Corticosteroids are used in approximately 50% of palliative care patients. Increasingly corticosteroids are used as local infiltrations together with local anaesthetics. This treatment may be adjuvant to other measures to control pain. Depo preparations, although their main activity is topical, may also exercise systemic toxicity. This may include transient suppression of adrenal activity which may be exacerbated by the use of morphine. Some women in reproductive age may experience vaginal blood loss between the periods. Other toxicities are rare.

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Keywords

corticosteroids; methylprednisolone acetate; triamcinolone acetonide; triamcinolone hexacetonide; depo preparations; adrenal suppression

About this article
Title

The systemic effects of local infiltrations with corticosteroids. Implications for palliative care?

Journal

Advances in Palliative Medicine

Issue

Vol 11, No 2 (2012)

Pages

74-77

Published online

2013-03-15

Page views

549

Article views/downloads

2147

Bibliographic record

Advances in Palliative Medicine 2012;11(2):74-77.

Keywords

corticosteroids
methylprednisolone acetate
triamcinolone acetonide
triamcinolone hexacetonide
depo preparations
adrenal suppression

Authors

Zbigniew Zylicz

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