Shortcuts

open access

Vol 1, No 1 (2002): Polish Palliative Medicine
Artykuły poglądowe
Published online: 2002-05-07
Get Citation

Radiation therapy for palliation of bone metastases

Roman Makarewicz, Jacek Fijuth
Advances in Palliative Medicine 2002;1(1):23-28.

open access

Vol 1, No 1 (2002): Polish Palliative Medicine
Artykuły poglądowe
Published online: 2002-05-07

Abstract

Patients with painful bone metastases comprise the largest group of patients receiving palliative radiation therapy. Effective administration of radiotherapy in these patients is based on three goals: to achieve relief of pain, to use treatment that reconciles patient inconvenience and to administer therapy with minimal toxic effects. Recent data from randomized trials demonstrated that single dose of 8 Gy in the setting of painful bone metastases may provide pain control comparable to more protracted treatment with using higher dose of radiation. Local-field irradiation with using single fraction of 8–10 Gy yields a pain relief rate of 75–90%, but patients frequently need retreatment for newly lesions or for recuring symptoms at the same site. The rate of retreatment is lower when protracted radiotherapy is used. Pain due to multiple bone metastases can be managed with single doses of half body irradiation or radionuclide therapy. These modalities can be used as a primary palliative therapy or as an adjuvant to local-field irradiation.

Abstract

Patients with painful bone metastases comprise the largest group of patients receiving palliative radiation therapy. Effective administration of radiotherapy in these patients is based on three goals: to achieve relief of pain, to use treatment that reconciles patient inconvenience and to administer therapy with minimal toxic effects. Recent data from randomized trials demonstrated that single dose of 8 Gy in the setting of painful bone metastases may provide pain control comparable to more protracted treatment with using higher dose of radiation. Local-field irradiation with using single fraction of 8–10 Gy yields a pain relief rate of 75–90%, but patients frequently need retreatment for newly lesions or for recuring symptoms at the same site. The rate of retreatment is lower when protracted radiotherapy is used. Pain due to multiple bone metastases can be managed with single doses of half body irradiation or radionuclide therapy. These modalities can be used as a primary palliative therapy or as an adjuvant to local-field irradiation.
Get Citation

Keywords

pain; metastases; radiotherapy

About this article
Title

Radiation therapy for palliation of bone metastases

Journal

Advances in Palliative Medicine

Issue

Vol 1, No 1 (2002): Polish Palliative Medicine

Pages

23-28

Published online

2002-05-07

Bibliographic record

Advances in Palliative Medicine 2002;1(1):23-28.

Keywords

pain
metastases
radiotherapy

Authors

Roman Makarewicz
Jacek Fijuth

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl