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Vol 2, No 3 (2003): Polish Palliative Medicine
Leki w medycynie paliatywnej
Published online: 2003-05-29
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Prokinetics in palliative care

Anna Adamczyk
Advances in Palliative Medicine 2003;2(3):199-202.

open access

Vol 2, No 3 (2003): Polish Palliative Medicine
Leki w medycynie paliatywnej
Published online: 2003-05-29

Abstract

Prokinetics accelerate gastric emptying and intestinal transit by interaction with neurohumoral pathways. Currently used prokinetics include: D2 receptor antagonists - domperidone and metoclopramide, 5-HT4 receptor agonists - cisapride and metoclopramide and motilin agonist - erythromycin. Indications for prokinetics in palliative care are nausea and vomiting caused by gastrostasis, gastro-oesophageal reflux, functional bowel obstruction, constipation, gastroparesis and irritable bowel syndrome.

Abstract

Prokinetics accelerate gastric emptying and intestinal transit by interaction with neurohumoral pathways. Currently used prokinetics include: D2 receptor antagonists - domperidone and metoclopramide, 5-HT4 receptor agonists - cisapride and metoclopramide and motilin agonist - erythromycin. Indications for prokinetics in palliative care are nausea and vomiting caused by gastrostasis, gastro-oesophageal reflux, functional bowel obstruction, constipation, gastroparesis and irritable bowel syndrome.

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Keywords

prokinetics; receptor D2 antagonist; receptor 5-HT4 agonist; motilin

About this article
Title

Prokinetics in palliative care

Journal

Advances in Palliative Medicine

Issue

Vol 2, No 3 (2003): Polish Palliative Medicine

Pages

199-202

Published online

2003-05-29

Page views

555

Article views/downloads

6406

Bibliographic record

Advances in Palliative Medicine 2003;2(3):199-202.

Keywords

prokinetics
receptor D2 antagonist
receptor 5-HT4 agonist
motilin

Authors

Anna Adamczyk

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