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Vol 4, No 1 (2005): Polish Palliative Medicine
Original articles
Published online: 2005-01-19
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Fluvoxamine efficacy in severe, dry cough in neoplasmatic diseases

Feliks Błaszczyk, Anna Orońska, Małgorzata Krajnik, Zbigniew Żylicz
Advances in Palliative Medicine 2005;4(1):17-20.

open access

Vol 4, No 1 (2005): Polish Palliative Medicine
Original articles
Published online: 2005-01-19

Abstract

Introduction. Dry cough may complicate many specific and non specific lung diseases including malignancies. Recently it was suggested that paroxetine, drug known for its antidepressive properties, can effectively inhibit dry cough without affecting expectoration. The aim of this study was to confirm or reject the notion that this effect is specific to paroxetine or it can be extended to the whole group of specific serotonin reuptake inhibitors.
Material and methods. Fluvoxamine 50 mg o.d. was administered to 6 patients who were suffering dry cough.
Results. Cough inhibition was seen in all 6 patients, but it was full only in the first day. Later on, during the follow up, cough intensity was about half the intensity from before the treatment.
Conclusion. It is not known whether the drug is truly weaker than paroxetine or its dose was too low.

Abstract

Introduction. Dry cough may complicate many specific and non specific lung diseases including malignancies. Recently it was suggested that paroxetine, drug known for its antidepressive properties, can effectively inhibit dry cough without affecting expectoration. The aim of this study was to confirm or reject the notion that this effect is specific to paroxetine or it can be extended to the whole group of specific serotonin reuptake inhibitors.
Material and methods. Fluvoxamine 50 mg o.d. was administered to 6 patients who were suffering dry cough.
Results. Cough inhibition was seen in all 6 patients, but it was full only in the first day. Later on, during the follow up, cough intensity was about half the intensity from before the treatment.
Conclusion. It is not known whether the drug is truly weaker than paroxetine or its dose was too low.
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Keywords

fluvoxamine; dry cough; cough inhibition; antitussive effect

About this article
Title

Fluvoxamine efficacy in severe, dry cough in neoplasmatic diseases

Journal

Advances in Palliative Medicine

Issue

Vol 4, No 1 (2005): Polish Palliative Medicine

Pages

17-20

Published online

2005-01-19

Bibliographic record

Advances in Palliative Medicine 2005;4(1):17-20.

Keywords

fluvoxamine
dry cough
cough inhibition
antitussive effect

Authors

Feliks Błaszczyk
Anna Orońska
Małgorzata Krajnik
Zbigniew Żylicz

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