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Vol 4, No 2 (2005): Polish Palliative Medicine
Original articles
Published online: 2005-05-04
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The assessment of the efficacy of high dose rate brachyterapy in the treatment of patients with advanced esophageal cancer comparison of three palliative radiotherapy methods

Joanna Terlikiewicz
Advances in Palliative Medicine 2005;4(2):53-66.

open access

Vol 4, No 2 (2005): Polish Palliative Medicine
Original articles
Published online: 2005-05-04

Abstract

The main symptoms in patients with advanced esophageal cancer are dysphagia, pain and weakness. The aim of this paper was to assess the efficacy of three radiotherapy methods in decreasing these symptoms. 110 patients with advanced esophageal cancer were treated with brachytherapy (BTH), teleradiotherapy (TRTH) or both methods (BTH + TRTH). Dysphagia and performance status were assessed using WHO scale and the quality of life with Rotterdam Symptom Check List. Median survival and survival free of dysphagia were assessed using Kaplan-Meier method. The improvement of dysphagia, pain and performance status were observed in next weeks after treatment. The quality of life was statistically better after the treatment. A significant difference in median survival and no differences in median survival free of dysphagia were observed.
Three radiotherapy methods were successful in palliative treatment of patients with advanced esophageal cancer. There were no differences between groups in decreasing the main symptoms due to advanced esophageal cancer.

Abstract

The main symptoms in patients with advanced esophageal cancer are dysphagia, pain and weakness. The aim of this paper was to assess the efficacy of three radiotherapy methods in decreasing these symptoms. 110 patients with advanced esophageal cancer were treated with brachytherapy (BTH), teleradiotherapy (TRTH) or both methods (BTH + TRTH). Dysphagia and performance status were assessed using WHO scale and the quality of life with Rotterdam Symptom Check List. Median survival and survival free of dysphagia were assessed using Kaplan-Meier method. The improvement of dysphagia, pain and performance status were observed in next weeks after treatment. The quality of life was statistically better after the treatment. A significant difference in median survival and no differences in median survival free of dysphagia were observed.
Three radiotherapy methods were successful in palliative treatment of patients with advanced esophageal cancer. There were no differences between groups in decreasing the main symptoms due to advanced esophageal cancer.
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Keywords

advanced esophageal cancer; brachytherapy; teleradiotherapy; dysphagia; quality of life

About this article
Title

The assessment of the efficacy of high dose rate brachyterapy in the treatment of patients with advanced esophageal cancer comparison of three palliative radiotherapy methods

Journal

Advances in Palliative Medicine

Issue

Vol 4, No 2 (2005): Polish Palliative Medicine

Pages

53-66

Published online

2005-05-04

Bibliographic record

Advances in Palliative Medicine 2005;4(2):53-66.

Keywords

advanced esophageal cancer
brachytherapy
teleradiotherapy
dysphagia
quality of life

Authors

Joanna Terlikiewicz

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