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Vol 5, No 1 (2006): Polish Palliative Medicine
Original articles
Published online: 2006-04-21
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Efficacy of videothoracoscopic talc pleurodesis and intrapleural administration of Vibramicin in palliative treatment of neoplasmatic pleural effusion - a comparative study

Paweł W. Kasprzak, Wojciech Dyszkiewicz
Advances in Palliative Medicine 2006;5(1):3-8.

open access

Vol 5, No 1 (2006): Polish Palliative Medicine
Original articles
Published online: 2006-04-21

Abstract

Background. Recurrent pleural effusion is a common finding in patients with primary or metastatic pulmonary neoplasm which worsen their quality of life at the end-stage disease. The aim of our study was the assessment of two comparable methods of pleurodesis.
Material and methods. In group I (n = 45) videothoracoscopic approach was used for evacuation of the fluid and talc poudrage. In group II (n = 30) pleural effusion was evacuated with chest tubing. When the lung was fully expanded chest tubes were used for rinsing of pleural space with Vibramycin.
Results and conclusion. Both methods showed comparable efficacy and 65% of patients at the third month of follow-up were free from pleural effusion. However, in group I (videothoracoscopic talc poudrage) recurrence rate of effusion was markedly lower than in group II (Vibramycin in pleural rinsing) (22% vs. 33%). We conclude that the use of videothoracoscopic talc poudrage provides longer and better results of pleurodesis than administration of Vibramycin to the pleural space.

Abstract

Background. Recurrent pleural effusion is a common finding in patients with primary or metastatic pulmonary neoplasm which worsen their quality of life at the end-stage disease. The aim of our study was the assessment of two comparable methods of pleurodesis.
Material and methods. In group I (n = 45) videothoracoscopic approach was used for evacuation of the fluid and talc poudrage. In group II (n = 30) pleural effusion was evacuated with chest tubing. When the lung was fully expanded chest tubes were used for rinsing of pleural space with Vibramycin.
Results and conclusion. Both methods showed comparable efficacy and 65% of patients at the third month of follow-up were free from pleural effusion. However, in group I (videothoracoscopic talc poudrage) recurrence rate of effusion was markedly lower than in group II (Vibramycin in pleural rinsing) (22% vs. 33%). We conclude that the use of videothoracoscopic talc poudrage provides longer and better results of pleurodesis than administration of Vibramycin to the pleural space.
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Keywords

lung cancer; pulmonary metastases; hydrothorax; pleurodesis

About this article
Title

Efficacy of videothoracoscopic talc pleurodesis and intrapleural administration of Vibramicin in palliative treatment of neoplasmatic pleural effusion - a comparative study

Journal

Advances in Palliative Medicine

Issue

Vol 5, No 1 (2006): Polish Palliative Medicine

Pages

3-8

Published online

2006-04-21

Bibliographic record

Advances in Palliative Medicine 2006;5(1):3-8.

Keywords

lung cancer
pulmonary metastases
hydrothorax
pleurodesis

Authors

Paweł W. Kasprzak
Wojciech Dyszkiewicz

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