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Advances in Palliative Medicine
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open access

Vol 6, No 3 (2007)
Case reports
Published online: 2007-11-07
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Difficulties in management of tuberculous pneumonia in a patient with liver failure in the course of chronic hepatitis B and concomitant failure of the transplanted kidney

Krzysztof Kuziemski, Marcin Skrzypski, Jan Marek Słomiński, Ewa Jassem
Advances in Palliative Medicine 2007;6(3):111-114.

open access

Vol 6, No 3 (2007)
Case reports
Published online: 2007-11-07

Abstract

A 62-year-old woman with liver failure in the course of chronic hepatitis B and concomitant failure of the transplanted kidney was treated for tuberculous pneumonia. The treatment was initiated with rifampin, isoniazid and pyrazinamide. Both renal and hepatic side effects required modification of this scheme. After 1 month of treatment sputum smears tested for acid-fast bacilli converted to a negative result and the chest X-ray demonstrated complete resolution of pulmonary infiltrates. Further therapy resulted in serious deterioration of the liver failure and fatal outcome.

Abstract

A 62-year-old woman with liver failure in the course of chronic hepatitis B and concomitant failure of the transplanted kidney was treated for tuberculous pneumonia. The treatment was initiated with rifampin, isoniazid and pyrazinamide. Both renal and hepatic side effects required modification of this scheme. After 1 month of treatment sputum smears tested for acid-fast bacilli converted to a negative result and the chest X-ray demonstrated complete resolution of pulmonary infiltrates. Further therapy resulted in serious deterioration of the liver failure and fatal outcome.

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Keywords

tuberculosis; antituberculous agents; liver failure; renal failure

About this article
Title

Difficulties in management of tuberculous pneumonia in a patient with liver failure in the course of chronic hepatitis B and concomitant failure of the transplanted kidney

Journal

Advances in Palliative Medicine

Issue

Vol 6, No 3 (2007)

Pages

111-114

Published online

2007-11-07

Page views

546

Article views/downloads

1123

Bibliographic record

Advances in Palliative Medicine 2007;6(3):111-114.

Keywords

tuberculosis
antituberculous agents
liver failure
renal failure

Authors

Krzysztof Kuziemski
Marcin Skrzypski
Jan Marek Słomiński
Ewa Jassem

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