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Problems of palliative care in patients with multiple myeloma
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Abstract
Material and methods. The trial included patients of home hospice care and the patients of a Palliative Care Ward. Retrospective analysis based on medical documentation was applied and, in patients that were still on treatment, prospective observation was conducted.
Results. The analysis included four patients on chemotherapy and two patients for whom intensive oncological treatment had been discontinued. The most frequent symptoms were afflictions connected to bone pain. These were often accompanied by secondary neurological symptoms of pathological bone fractures or compressions caused directly by the neoplastic tumour and symptoms of peripheral neuropathy. Secondary nephropathy (myelomic kidney) and a tendency to hypercalcaemia occurred. Various symptoms of blood hyperviscosity syndrome (dysfunctions of organs: kidneys, heart; bleeding gums and nose) were observed. Additionally during palliative care, it was essential to notice and counteract disease aggravations.
Conclusion. Patients with multiple myeloma constitute a great challenge in palliative care due to the changeable clinical course of the disease, repetitive relapses and remissions. Numerous symptoms of the disease require continuous observation and the proper treatment, which demonstrates that simultaneous multi-specialist care is essential.
Abstract
Material and methods. The trial included patients of home hospice care and the patients of a Palliative Care Ward. Retrospective analysis based on medical documentation was applied and, in patients that were still on treatment, prospective observation was conducted.
Results. The analysis included four patients on chemotherapy and two patients for whom intensive oncological treatment had been discontinued. The most frequent symptoms were afflictions connected to bone pain. These were often accompanied by secondary neurological symptoms of pathological bone fractures or compressions caused directly by the neoplastic tumour and symptoms of peripheral neuropathy. Secondary nephropathy (myelomic kidney) and a tendency to hypercalcaemia occurred. Various symptoms of blood hyperviscosity syndrome (dysfunctions of organs: kidneys, heart; bleeding gums and nose) were observed. Additionally during palliative care, it was essential to notice and counteract disease aggravations.
Conclusion. Patients with multiple myeloma constitute a great challenge in palliative care due to the changeable clinical course of the disease, repetitive relapses and remissions. Numerous symptoms of the disease require continuous observation and the proper treatment, which demonstrates that simultaneous multi-specialist care is essential.
Keywords
multiple myeloma (plasmocytoma); palliative care; chemotherapy; rehabilitation
Title
Problems of palliative care in patients with multiple myeloma
Journal
Advances in Palliative Medicine
Issue
Pages
137-146
Published online
2008-02-20
Page views
629
Article views/downloads
3986
Bibliographic record
Advances in Palliative Medicine 2007;6(4):137-146.
Keywords
multiple myeloma (plasmocytoma)
palliative care
chemotherapy
rehabilitation
Authors
Michał Graczyk
Anna Pyszora
Małgorzata Krajnik