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Advances in Palliative Medicine
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open access

Vol 7, No 1 (2008)
Original articles
Published online: 2008-02-25
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The potential influence of the applied treatment on selected endocrine and non endocrine parameters and general status of the patients with cancer cachexia syndrome

Maciej Bączyk, Lidia Gorzelińska, Marlena Pisarek, Paweł Gut, Jerzy Sowiński, Jacek Łuczak
Advances in Palliative Medicine 2008;7(1):9-14.

open access

Vol 7, No 1 (2008)
Original articles
Published online: 2008-02-25

Abstract

The aim of the study was to establish correlation between the grade of cachexia and possible endocrine and non endocrine factors and the type of therapy (NSAID, corticosteroids, progestagens). 98 patients aged 36-70 years (mean - 55 years) with various degree of cancer cachexia were qualified to the study. Statistically significant, positive correlation between weight loss and: anorexia (p < 0.01), pain intensity (p < 0.01), grade of depression (p < 0.01), higher values of cortisol (p < 0.05) was detected. The progestagens are the most effective agents in the treatment of cancer cachexia, but good symptom control and psychological status of patient are also very important.

Abstract

The aim of the study was to establish correlation between the grade of cachexia and possible endocrine and non endocrine factors and the type of therapy (NSAID, corticosteroids, progestagens). 98 patients aged 36-70 years (mean - 55 years) with various degree of cancer cachexia were qualified to the study. Statistically significant, positive correlation between weight loss and: anorexia (p < 0.01), pain intensity (p < 0.01), grade of depression (p < 0.01), higher values of cortisol (p < 0.05) was detected. The progestagens are the most effective agents in the treatment of cancer cachexia, but good symptom control and psychological status of patient are also very important.

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Keywords

cancer cachexia; cortisol; cytokines; progestagens

About this article
Title

The potential influence of the applied treatment on selected endocrine and non endocrine parameters and general status of the patients with cancer cachexia syndrome

Journal

Advances in Palliative Medicine

Issue

Vol 7, No 1 (2008)

Pages

9-14

Published online

2008-02-25

Page views

695

Article views/downloads

954

Bibliographic record

Advances in Palliative Medicine 2008;7(1):9-14.

Keywords

cancer cachexia
cortisol
cytokines
progestagens

Authors

Maciej Bączyk
Lidia Gorzelińska
Marlena Pisarek
Paweł Gut
Jerzy Sowiński
Jacek Łuczak

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