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Advances in Palliative Medicine
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open access

Vol 8, No 3 (2009)
Review articles
Published online: 2009-11-02
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Antithrombotic therapy in palliative care

Miriam J. Johnson, Simon I.R. Noble, Anthony Maraveyas
Advances in Palliative Medicine 2009;8(3):95-100.

open access

Vol 8, No 3 (2009)
Review articles
Published online: 2009-11-02

Abstract

Management of venous thromboembolism (VTE) in patients in advanced cancer can be difficult due to the increased risk of recurrent and extending VTE despite therapeutic anticoagulation, and of bleeding due to or exacerbated by anticoagulation. Currently, best practice is long term administration of low molecular weight heparin (LMWH), but a recurrent VTE and bleeding rate remains, and some patients have contra-indications to anticoagulation. Newer anticoagulants such as oral anti-thrombin agents and biotinylated idrapurinux may have a role in the future.

Abstract

Management of venous thromboembolism (VTE) in patients in advanced cancer can be difficult due to the increased risk of recurrent and extending VTE despite therapeutic anticoagulation, and of bleeding due to or exacerbated by anticoagulation. Currently, best practice is long term administration of low molecular weight heparin (LMWH), but a recurrent VTE and bleeding rate remains, and some patients have contra-indications to anticoagulation. Newer anticoagulants such as oral anti-thrombin agents and biotinylated idrapurinux may have a role in the future.

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Keywords

palliative care; cancer; low molecular weight heparin; anticoagulation

About this article
Title

Antithrombotic therapy in palliative care

Journal

Advances in Palliative Medicine

Issue

Vol 8, No 3 (2009)

Pages

95-100

Published online

2009-11-02

Page views

648

Article views/downloads

2775

Bibliographic record

Advances in Palliative Medicine 2009;8(3):95-100.

Keywords

palliative care
cancer
low molecular weight heparin
anticoagulation

Authors

Miriam J. Johnson
Simon I.R. Noble
Anthony Maraveyas

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