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open access

Vol 8, No 4 (2009)
Case reports
Published online: 2010-02-01
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Effectiveness of octreotide in advanced cancer patients with malignant bowel obstruction and intractable diarrhea

Tomasz Grądalski, Izabela Bętkowska
Advances in Palliative Medicine 2009;8(4):161-164.

open access

Vol 8, No 4 (2009)
Case reports
Published online: 2010-02-01

Abstract

Malignant bowel obstruction and intractable diarrhea in advanced cancer are common devastating syndromes. Apart from disease specific, causative treatment in patients with longer prognosis, there is a possibility of conservative, non-operative symptom management in terminal phase. A successful control of intractable vomiting and diarrhea using octreotide in two advanced cancer patients was presented, with guidance through steps of the management. Pathophysiologic vicious circle of the bowel obstruction and diarrhoea was described and the management algorithm was proposed. Due to the gut hyposecreting action, octreotide occurs to be a potent and essential drug in refractory vomiting or diarrhea.

Abstract

Malignant bowel obstruction and intractable diarrhea in advanced cancer are common devastating syndromes. Apart from disease specific, causative treatment in patients with longer prognosis, there is a possibility of conservative, non-operative symptom management in terminal phase. A successful control of intractable vomiting and diarrhea using octreotide in two advanced cancer patients was presented, with guidance through steps of the management. Pathophysiologic vicious circle of the bowel obstruction and diarrhoea was described and the management algorithm was proposed. Due to the gut hyposecreting action, octreotide occurs to be a potent and essential drug in refractory vomiting or diarrhea.
Get Citation

Keywords

malignant bowel obstruction; intractable diarrhea; octreotide

About this article
Title

Effectiveness of octreotide in advanced cancer patients with malignant bowel obstruction and intractable diarrhea

Journal

Advances in Palliative Medicine

Issue

Vol 8, No 4 (2009)

Pages

161-164

Published online

2010-02-01

Bibliographic record

Advances in Palliative Medicine 2009;8(4):161-164.

Keywords

malignant bowel obstruction
intractable diarrhea
octreotide

Authors

Tomasz Grądalski
Izabela Bętkowska

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