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open access

Vol 11, No 1 (2012)
Case reports
Published online: 2012-11-02
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A patient with intractable pain on high dose opioid therapy. Could we manage not to escalate the opioid dose?

Piotr Sobanski, Malgorzata Krajnik, Lucas Ritz, Felix Schläfli, Jan Kobialka, Zbigniew Zylicz
Advances in Palliative Medicine 2012;11(1):36-40.

open access

Vol 11, No 1 (2012)
Case reports
Published online: 2012-11-02

Abstract

Prolonged opioid treatment reveals problems, like opioid tolerance and opioid induced hyperalgesia. On every stage of disease it should be remembered to use procedures that can have opioid dose sparing effect. We describe a patient with severe mixed neuropathic and nociceptive pain who despite complex medication embracing high dose of morphine suffered from untractable pain. He responded to opioid antagonist with sequential opioid rotation and a simple minimally invasive procedure.

Abstract

Prolonged opioid treatment reveals problems, like opioid tolerance and opioid induced hyperalgesia. On every stage of disease it should be remembered to use procedures that can have opioid dose sparing effect. We describe a patient with severe mixed neuropathic and nociceptive pain who despite complex medication embracing high dose of morphine suffered from untractable pain. He responded to opioid antagonist with sequential opioid rotation and a simple minimally invasive procedure.
Get Citation

Keywords

mixed cancer pain syndrome; opioid induced hyperalgesia; opioid rotation; opioid antagonist

About this article
Title

A patient with intractable pain on high dose opioid therapy. Could we manage not to escalate the opioid dose?

Journal

Advances in Palliative Medicine

Issue

Vol 11, No 1 (2012)

Pages

36-40

Published online

2012-11-02

Bibliographic record

Advances in Palliative Medicine 2012;11(1):36-40.

Keywords

mixed cancer pain syndrome
opioid induced hyperalgesia
opioid rotation
opioid antagonist

Authors

Piotr Sobanski
Malgorzata Krajnik
Lucas Ritz
Felix Schläfli
Jan Kobialka
Zbigniew Zylicz

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