Vol 55, No 2 (2024)
Clinical vignette
Published online: 2024-03-01

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Allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia with an accompanying hereditary hemorrhagic telangiectasia

Daniel Habraszka1, Szymon Gawęda1, Adrianna Spałek2, Grzegorz Helbig2
Acta Haematol Pol 2024;55(2):123-125.


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  1. McDonald J, Bayrak-Toydemir P, Pyeritz RE. Hereditary hemorrhagic telangiectasia: an overview of diagnosis, management, and pathogenesis. Genet Med. 2011; 13(7): 607–616.
  2. Sadick H, Riedel F, Naim R, et al. Patients with hereditary hemorrhagic telangiectasia have increased plasma levels of vascular endothelial growth factor and transforming growth factor-beta1 as well as high ALK1 tissue expression. Haematologica. 2005; 90(6): 818–828.
  3. Viteri-Noël A, González-García A, Patier JL, et al. Hereditary hemorrhagic telangiectasia: genetics, pathophysiology, diagnosis, and management. J Clin Med. 2022; 11(17): 5245.
  4. Shovlin C, Guttmacher A, Buscarini E, et al. Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome). American Journal of Medical Genetics. 2000; 91(1): 66–67, doi: 10.1002/(sici)1096-8628(20000306)91:1<66::aid-ajmg12>3.0.co;2-p.
  5. Kjeldsen AD, Vase P, Green A. Hereditary haemorrhagic telangiectasia: a population-based study of prevalence and mortality in Danish patients. J Intern Med. 1999; 245(1): 31–39.
  6. Letteboer TGW, Mager JJ, Snijder RJ, et al. Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia. J Med Genet. 2006; 43(4): 371–377.
  7. Williams JCB, Hamilton JK, Shiller M, et al. Combined juvenile polyposis and hereditary hemorrhagic telangiectasia. Proc (Bayl Univ Med Cent). 2012; 25(4): 360–364.
  8. Mazharian A, Ghevaert C, Zhang L, et al. Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation. Blood. 2011; 117(19): 5198–5206.
  9. Sartor C, Papayannidis C, Chiara Abbenante M, et al. Recurrent gastrointestinal hemorrhage in treatment with dasatinib in a patient showing SMAD4 mutation with acute lymphoblastic leukemia Philadelphia positive and juvenile polyposis hereditary hemorrhagic telangiectasia syndrome. Hematol Rep. 2013; 5(2): 26–27.