Vol 55, No 2 (2024)
Clinical vignette
Published online: 2024-03-05

open access

Page views 176
Article views/downloads 146
Get Citation

Connect on Social Media

Connect on Social Media

Multidrug rescue for pediatric refractory ITP complicated by intracranial bleeding

Bartosz Urbański1, Olga Wegner1, Ewelina Subocz1, Monika Zjawiona1, Magdalena Wojdalska1, Dobromiła Barańska2, Wojciech Młynarski1, Szymon Janczar1
Acta Haematol Pol 2024;55(2):126-128.


Not available

Article available in PDF format

View PDF Download PDF file


  1. Miltiadous O, Hou M, Bussel JB. Identifying and treating refractory ITP: difficulty in diagnosis and role of combination treatment. Blood. 2020; 135(7): 472–490.
  2. Neunert C, Heitink-Polle KMJ, Lambert MP. A proposal for new definition (s) and management approach to paediatric refractory ITP: Reflections from the Intercontinental ITP Study Group. Br J Haematol. 2023; 203(1): 17–22.
  3. Neunert C, Terrell DR, Arnold DM, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019; 3(23): 3829–3866.
  4. Ibrahim L, Dong SX, O'Hearn K, et al. Pediatric refractory immune thrombocytopenia: A systematic review. Pediatr Blood Cancer. 2023; 70(3): e30173.
  5. Vianelli N, Auteri G, Buccisano F, et al. Refractory primary immune thrombocytopenia (ITP): current clinical challenges and therapeutic perspectives. Ann Hematol. 2022; 101(5): 963–978.
  6. Kjeldsen-Kragh J, Fergusson DA, Kjaer M, et al. Fetal/neonatal alloimmune thrombocytopenia: a systematic review of impact of HLA-DRB3*01:01 on fetal/neonatal outcome. Blood Adv. 2020; 4(14): 3368–3377.
  7. Zheng SS, Ahmadi Z, Leung HH, et al. Antiplatelet antibody predicts platelet desialylation and apoptosis in immune thrombocytopenia. Haematologica. 2022; 107(9): 2195–2205.
  8. Marini I, Zlamal J, Faul C, et al. Autoantibody-mediated desialylation impairs human thrombopoiesis and platelet lifespan. Haematologica. 2021; 106(1): 196–207.
  9. Zheng SS, Perdomo JS, Leung HH, et al. Acquired Glanzmann thrombasthenia associated with platelet desialylation. J Thromb Haemost. 2020; 18(3): 714–721.
  10. Kochhar M, Neunert C. Immune thrombocytopenia: A review of upfront treatment strategies. Blood Rev. 2021; 49: 100822.