Vol 46, No 3 (2015)
Prace poglądowe / Reviews
Published online: 2015-05-01

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Recommendations of Polish Myeloma Group concerning diagnosis and therapy of multiple myeloma and other plasmacytic dyscrasias for 2015

Anna Dmoszyńska1, Adam Walter-Croneck2, Lidia Usnarska-Zubkiewicz3, Beata Stella-Hołowiecka4, Jan Walewski5, Grzegorz Charliński6, Wiesław Wiktor Jędrzejczak6, Elżbieta Wiater7, Ewa Lech-Marańda8, Dominik Dytfeld9, Mieczysław Komarnicki9, Krzysztof Jamroziak8, Tadeusz Robak10, Artur Jurczyszyn11, Joanna Mańko2, Aleksander Skotnicki11, Sebastian Giebel12, Iwona Hus12, Ryszard Czepko13, Janusz Meder14, Bogdan Małkowski15, Krzysztof Giannopoulos216
DOI: 10.1016/j.achaem.2015.04.004
Acta Haematol Pol 2015;46(3):159-211.

Abstract

New drugs introduced in recent years to the therapy of multiple myeloma patients resulted in better responses and prolongation of overall survival. Therapeutic regimens based on bortezomib, thalidomide and lenalidomide are recommended to most patients in first line therapy. Induction therapy should be accompanied with prolonged treatment composed of consolidation and maintenance. Besides the concept of longer treatment, it is recommended to start therapy in some patients earlier, taking into consideration biomarkers of active disease as well as transplantation procedure offered to older, fit patients. In this article we also described therapeutic recommendation for Waldenström macroglobulinemia and other plasmocytic dyscrasias.

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