Vol 47, No 2 (2016)
Prace poglądowe / Reviews
Published online: 2016-04-01

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Recommendations of Polish Myeloma Group concerning diagnosis and therapy of multiple myeloma and other plasmacytic dyscrasias for 2016

Anna Dmoszyńska1, Adam Walter-Croneck2, Barbara Pieńkowska-Grela3, Lidia Usnarska-Zubkiewicz4, Jan Walewski5, Grzegorz Charliński6, Wiesław Wiktor Jędrzejczak7, Elżbieta Wiater8, Ewa Lech-Marańda9, Krzysztof Jamroziak9, Agnieszka Druzd-Sitek5, Dominik Dytfeld10, Mieczysław Komarnicki10, Tadeusz Robak11, Artur Jurczyszyn12, Joanna Mańko2, Aleksander Skotnicki12, Sebastian Giebel13, Ryszard Czepko14, Janusz Meder15, Bogdan Małkowski16, Krzysztof Giannopoulos1718
DOI: 10.1016/j.achaem.2016.04.010
Acta Haematol Pol 2016;47(2):39-85.

Abstract

New drugs introduced in recent years for the therapy of multiple myeloma patients resulted in better responses and prolongation of overall survival. While therapeutic regimens based on bortezomib and thalidomide are recommended to most patients in first-line therapy, lenalidomide represents a cornerstone for treatment of relapsed/refractory myeloma patients. Most patients profit from prolonged treatment composed of consolidation and maintenance or treatment till progression. Beside concept of longer treatment, it is recommended to start therapy in some patients earlier, taking into consideration biomarkers of active disease. In this article, we described also therapeutic recommendation for Waldenström macroglobulinemia and other plasmocytic dyscrasias.

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