Vol 45, No 1 (2014)
Kazuistyka / Case reports
Published online: 2014-01-01

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Kikuchi-Fujimoto disease: report of two new Polish cases and review of the current literature

Agata Tyczyńska1, Agnieszka Giza2, Anna Kalicka3, Paweł Pikiel4, Jacek Kowalski3, Krzysztof Leśniewski-Kmak15, Aleksander Skotnicki2, Jan Maciej Zaucha15
DOI: 10.1016/j.achaem.2013.11.003
Acta Haematol Pol 2014;45(1):101-106.

Abstract

Kikuchi-Fujimoto disease (KFD, histiocytic necrotizing lymphadenitis) is benign and self-limited cervical lymphadenopathy with accompanied mild fever. Disorder mostly affects young adults, rarely children mainly in Asia. The etiology of KFD is unknown but it is thought to be an autoimmune or inflammatory process triggered by viral infection in susceptible individuals. The minimal criteria required for the diagnosis of KFD include the presence of paracortical clusters of plasmacytoid dendritic cells admixed with karyorrhectic bodies and crescentic histiocytes. KFD does not require specific treatment except from antipyretics and anti-inflammatory medications. Here we present two new cases of KFD described in Poland together with the review of current literature.

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