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Diagnosis and differentiation of late non-infectious pulmonary complications after allogeneic haematopoietic stem cell transplantation
Affiliations- Katedra i Klinika Hematologii i Chorób Rozrostowych Układu Krwiotwórczego Uniwersytetu Medycznego, Kierownik: prof. dr hab. Mieczysław Komarnicki, Poznań, Polska
- Katedra i Klinika Pulmonologii, Alergologii i Onkologii Pulmonologicznej Uniwersytetu Medycznego, Kierownik: prof. dr hab. med. Halina Batura-Gabryel, Poznań, Polska
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Abstract
The role of pulmonary function monitoring after allogeneic haematopoietic stem cell transplantation and the prognostic significance of detected airflow impairment are discussed by the authors. The purpose of the work is also to clarify the nomenclature and diagnostic criteria of non-infectious pulmonary complications after allotransplant. The incidence and diagnostic criteria of representative conditions, as bronchiolitis obliterans and cryptogenic organizing pneumonia are presented. The significance of radiologic findings, bronchoscopy and lung biopsy in diagnostic strategy is also discussed. We believe that the presented review of the current multidisciplinary knowledge on late non-infectious pulmonary complications in patients after stem cell transplantation may be useful in improving the quality of long-term care of those patients.
Abstract
The role of pulmonary function monitoring after allogeneic haematopoietic stem cell transplantation and the prognostic significance of detected airflow impairment are discussed by the authors. The purpose of the work is also to clarify the nomenclature and diagnostic criteria of non-infectious pulmonary complications after allotransplant. The incidence and diagnostic criteria of representative conditions, as bronchiolitis obliterans and cryptogenic organizing pneumonia are presented. The significance of radiologic findings, bronchoscopy and lung biopsy in diagnostic strategy is also discussed. We believe that the presented review of the current multidisciplinary knowledge on late non-infectious pulmonary complications in patients after stem cell transplantation may be useful in improving the quality of long-term care of those patients.
Keywords
Allogeneic haematopoietic stem cell transplantation; Pulmonary complications; Pulmonary function tests
About this articleTitle
Diagnosis and differentiation of late non-infectious pulmonary complications after allogeneic haematopoietic stem cell transplantation
Journal
Issue
Pages
392-398
Published online
2013-10-01
Page views
98
Article views/downloads
281
DOI
10.1016/j.achaem.2013.04.001
Bibliographic record
Acta Haematol Pol 2013;44(4):392-398.
Keywords
Allogeneic haematopoietic stem cell transplantation
Pulmonary complications
Pulmonary function tests
Authors
Anna Czyż
Tomasz Piorunek
Szczepan Cofta
Mieczysław Komarnicki