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Risk of transmission of blood-derived pathogens by transfusion in Poland


- Zakład Wirusologii, Instytut Hematologii i Transfuzjologii w Warszawie, Polska
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Abstract
Blood transfusion in Poland is the safest in history. High virological level of safety has been achieved mainly by improving not only the qualification of donors and methods used for donor screening, but also applying leukoreduction, pathogen reduction technology and grace period for serum.
In this article, we discuss the improvement of the epidemic situation among blood donors for hepatitis B virus (HBV) and hepatitis C virus (HCV) and the increasing trend for HIV. Preliminary results of residual risk calculation for these pathogens are presented.
Hepatitis E virus (HEV) and Babesia microti were considered as new factors potentially relevant for the safety of blood transfusion in our country. Due to evidence of West Nile virus (WNV) circulation in the ecosystem in Poland, it is also necessary to monitor the infections with this pathogen.
In this article, it was emphasized that the reporting of all possible complications associated with transfusion and meticulous implementation of the look-back procedure play a key role for monitoring the risk of transmission of infectious agents by blood. It is especially important in view of the increasing epidemiological problems associated with emerging infectious agents.
Abstract
Blood transfusion in Poland is the safest in history. High virological level of safety has been achieved mainly by improving not only the qualification of donors and methods used for donor screening, but also applying leukoreduction, pathogen reduction technology and grace period for serum.
In this article, we discuss the improvement of the epidemic situation among blood donors for hepatitis B virus (HBV) and hepatitis C virus (HCV) and the increasing trend for HIV. Preliminary results of residual risk calculation for these pathogens are presented.
Hepatitis E virus (HEV) and Babesia microti were considered as new factors potentially relevant for the safety of blood transfusion in our country. Due to evidence of West Nile virus (WNV) circulation in the ecosystem in Poland, it is also necessary to monitor the infections with this pathogen.
In this article, it was emphasized that the reporting of all possible complications associated with transfusion and meticulous implementation of the look-back procedure play a key role for monitoring the risk of transmission of infectious agents by blood. It is especially important in view of the increasing epidemiological problems associated with emerging infectious agents.
Keywords
HCV; HBV; HIV; HEV; Babesia microti; Transfusion-transmitted pathogens


Title
Risk of transmission of blood-derived pathogens by transfusion in Poland
Journal
Issue
Pages
174-182
Published online
2017-07-01
Page views
123
Article views/downloads
392
DOI
10.1016/j.achaem.2017.07.006
Bibliographic record
Acta Haematol Pol 2017;48(3):174-182.
Keywords
HCV
HBV
HIV
HEV
Babesia microti
Transfusion-transmitted pathogens
Authors
Piotr Grabarczyk
Aneta Kopacz
Ewa Sulkowska
Aleksandra Kalińska