open access

Vol 51, No 4 (2020)
Untitled
Submitted: 2020-07-03
Published online: 2020-12-01
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Medical dilemmas – erythrocytosis

Krzysztof Lewandowski1
DOI: 10.2478/ahp-2020-0036
·
Acta Haematol Pol 2020;51(4):203-211.
Affiliations
  1. Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Szamarzewskiego 84, 60-569 Poznań, Poland

open access

Vol 51, No 4 (2020)
Untitled
Submitted: 2020-07-03
Published online: 2020-12-01

Abstract

Erythrocytosis is defined not only by an increase in the erythrocyte count, hemoglobin concentration, and hematocrit value, but also by the occurrence of specific symptoms, the intensity and frequency of which depend on the character of the initial genetic lesion. Ischemic episodes and thrombotic complications caused by increased blood viscosity are frequently the first clinical manifestation of the disease. This paper represents the current level of knowledge about the pathogenesis of erythrocytosis and the diagnostic algorithms used to precisely define the type of the disease.

Abstract

Erythrocytosis is defined not only by an increase in the erythrocyte count, hemoglobin concentration, and hematocrit value, but also by the occurrence of specific symptoms, the intensity and frequency of which depend on the character of the initial genetic lesion. Ischemic episodes and thrombotic complications caused by increased blood viscosity are frequently the first clinical manifestation of the disease. This paper represents the current level of knowledge about the pathogenesis of erythrocytosis and the diagnostic algorithms used to precisely define the type of the disease.

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Keywords

polycythemia; erythrocytosis; thrombosis; molecular defects; inflammation; therapy

About this article
Title

Medical dilemmas – erythrocytosis

Journal

Acta Haematologica Polonica

Issue

Vol 51, No 4 (2020)

Pages

203-211

Published online

2020-12-01

Page views

155

Article views/downloads

268

DOI

10.2478/ahp-2020-0036

Bibliographic record

Acta Haematol Pol 2020;51(4):203-211.

Keywords

polycythemia
erythrocytosis
thrombosis
molecular defects
inflammation
therapy

Authors

Krzysztof Lewandowski

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