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Abnormal hemostasis screening tests leading to diagnosis of multiple myeloma
Affiliations- Division of Molecular Biology and Clinical Genetics, Department of Medicine, Jagiellonian University Medical College, Krakow, Poland
- Department of Haematology, Jagiellonian University Medical College, Krakow, Poland
open access
Abstract
Multiple myeloma (MM) is a rare malignancy, characterized by clonal proliferation of plasma cells, secreting monoclonal immunoglobulin. It is usually diagnosed based on histopathologic and immunophenotypic bone marrow examination. Abnormal results of screening coagulation tests, including prothrombin time, activated partial thromboplastin time and thrombin time, are commonly encountered in patients with plasma cell neoplasms. They do not, however, reflect bleeding tendency. We describe a 71-year-old patient who was accidentally diagnosed with multiple myeloma during coagulation diagnostics.
Abstract
Multiple myeloma (MM) is a rare malignancy, characterized by clonal proliferation of plasma cells, secreting monoclonal immunoglobulin. It is usually diagnosed based on histopathologic and immunophenotypic bone marrow examination. Abnormal results of screening coagulation tests, including prothrombin time, activated partial thromboplastin time and thrombin time, are commonly encountered in patients with plasma cell neoplasms. They do not, however, reflect bleeding tendency. We describe a 71-year-old patient who was accidentally diagnosed with multiple myeloma during coagulation diagnostics.
Keywords
multiple myleoma; paraprotein; hemostasis screening test; thrombin time
About this articleTitle
Abnormal hemostasis screening tests leading to diagnosis of multiple myeloma
Journal
Issue
Pages
32-35
Published online
2019-05-08
Page views
183
Article views/downloads
801
DOI
10.2478/ahp-2019-0006
Bibliographic record
Acta Haematol Pol 2019;50(1):32-35.
Keywords
multiple myleoma
paraprotein
hemostasis screening test
thrombin time
Authors
Teresa Iwaniec
Joanna Zdziarska
Artur Jurczyszyn