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Przewlekłe leczenie przeciwkrzepliwe
Affiliations- Uniwersytet Medyczny im. K. Marcinkowskiego, Centrum Diagnostyczno-Lecznicze INTERLAB w Poznaniu, Poznań, Poland
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Abstract
Unprovoked venous thromboembolism (VTE) - proximal venous thrombosis or pulmonary embolism - should be treated either 3 months or indefinitely if the risk of bleeding is low. This article summarizes the efficacy and safety of extended therapy of VTE with direct oral anticoagulants (DOAC) in comparison with warfarin, as well as the role of of acetylsalicylic acid (ASA) for the long-term prevention of recurrent VTE. As the Survet study showed, for some patients who have already completed at least 6 months of anticoagulant treatment for their index VTE event, an oral glycosaminoglycan - sulodexide associated with compression therapy is a good choice, because it decreases the incidence of recurrences of VTE without detectable risks for the patients’ safety.
Abstract
Unprovoked venous thromboembolism (VTE) - proximal venous thrombosis or pulmonary embolism - should be treated either 3 months or indefinitely if the risk of bleeding is low. This article summarizes the efficacy and safety of extended therapy of VTE with direct oral anticoagulants (DOAC) in comparison with warfarin, as well as the role of of acetylsalicylic acid (ASA) for the long-term prevention of recurrent VTE. As the Survet study showed, for some patients who have already completed at least 6 months of anticoagulant treatment for their index VTE event, an oral glycosaminoglycan - sulodexide associated with compression therapy is a good choice, because it decreases the incidence of recurrences of VTE without detectable risks for the patients’ safety.
Keywords
Extended therapy of venous thromboembolism; VTE; direct oral anticoagulants; DOAC; acetylsalicylic acid; ASA; glycosaminoglycan
About this articleTitle
Przewlekłe leczenie przeciwkrzepliwe
Journal
Issue
Pages
47-49
Published online
2018-08-30
Page views
251
Article views/downloads
229
DOI
10.2478/ahp-2018-0009
Bibliographic record
Acta Haematol Pol 2018;49(2):47-49.
Keywords
Extended therapy of venous thromboembolism
VTE
direct oral anticoagulants
DOAC
acetylsalicylic acid
ASA
glycosaminoglycan
Authors
Krystyna Zawilska