Vol 49, No 1 (2018)
REVIEW ARTICLE
Published online: 2018-03-30

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Diagnostic approach to light-chain cardiac amyloidosis and its differential diagnosis

Monika Adamska1, Anna Komosa2, Tatiana Mularek2, Joanna Rupa-Matysek1, Lidia Gil1
DOI: 10.2478/ahp-2018-0002
Acta Haematol Pol 2018;49(1):9-14.

Abstract

Cardiac amyloidosis is a rare and often-misdiagnosed disorder. Among other forms of deposits affecting the heart, immunoglobulin-derived light-chain amyloidosis (AL amyloidosis) is the most serious form of the disease. Delay in diagnosis and treatment may have a major impact on the prognosis and outcomes of patients. This review focuses on the presentation of the disorder and current novel approaches to the diagnosis of cardiac involvement in AL amyloidosis.

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