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Possible interactions of fluoride, calcium, and fatty acids in atherosclerotic plaques
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Abstract
Material and methods. Plaques were obtained from patients operated for atherosclerosis of carotid arteries. Median content of fluoride and calcium in the atherosclerotic plaques were 0.75 and 207 μmol/g, respectively.
Results. No correlation between the content of fluoride and calcium (R = 0.11, p = 0.60) was disclosed.
Conclusions. We are of the opinion that fluoride reacts with fatty acids of the plaque, disrupting carbon bonds of the fatty acid molecule. Fluoride is a component of the atherosclerotic plaque but apparently is not deposited together with calcium ions. Fluoride is capable of interacting with fatty acids of the atherosclerotic plaque.
Abstract
Material and methods. Plaques were obtained from patients operated for atherosclerosis of carotid arteries. Median content of fluoride and calcium in the atherosclerotic plaques were 0.75 and 207 μmol/g, respectively.
Results. No correlation between the content of fluoride and calcium (R = 0.11, p = 0.60) was disclosed.
Conclusions. We are of the opinion that fluoride reacts with fatty acids of the plaque, disrupting carbon bonds of the fatty acid molecule. Fluoride is a component of the atherosclerotic plaque but apparently is not deposited together with calcium ions. Fluoride is capable of interacting with fatty acids of the atherosclerotic plaque.
Keywords
fluoride; calcium; fatty acids; atherosclerotic plaque
About this articleTitle
Possible interactions of fluoride, calcium, and fatty acids in atherosclerotic plaques
Journal
Issue
Article type
Research paper
Pages
151-157
Published online
2003-09-26
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592
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Bibliographic record
Acta Angiologica 2003;9(4):151-157.
Keywords
fluoride
calcium
fatty acids
atherosclerotic plaque
Authors
Ewa Stachowska
Dariusz Chlubek
Barbara Dołęgowska
Piotr Gutowski
Katarzyna Jakubowska
Iwona Noceń
Zygmunt Machoy
Halina Szumiłowicz
Miłosław Cnotliwy