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Local intra-arterial thrombolysis for peripheral arterial occlusion
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Abstract
Material and methods: From January to December 2003, 5 patients with femoro-popliteal occlusions were treated with local intra-arterial thrombolysis. All patients underwent a colour Doppler examination followed by angiography, which confirmed the diagnosis. A catheter was introduced through a femoral artery puncture and its tip was localized in the region of the artery occlusion. All patients obtained streptokinase. The progress of thrombolysis was monitored by repeated angiography and treatment was continued for up to 6 hours after the radiographically confirmed restoration of patency of the vessel.
Results: In all 5 treated patients we restored patency of the previously occluded artery and obtained complete remission of symptoms of lower limb ischaemia.
Conclusions: Local intra-arterial thrombolysis is a safe and effective method of treating lower limb ischaemia in selected patients. It allows for a decrease in the total dose of the thrombolytic agent and can be a good alternative to surgical procedure.
Abstract
Material and methods: From January to December 2003, 5 patients with femoro-popliteal occlusions were treated with local intra-arterial thrombolysis. All patients underwent a colour Doppler examination followed by angiography, which confirmed the diagnosis. A catheter was introduced through a femoral artery puncture and its tip was localized in the region of the artery occlusion. All patients obtained streptokinase. The progress of thrombolysis was monitored by repeated angiography and treatment was continued for up to 6 hours after the radiographically confirmed restoration of patency of the vessel.
Results: In all 5 treated patients we restored patency of the previously occluded artery and obtained complete remission of symptoms of lower limb ischaemia.
Conclusions: Local intra-arterial thrombolysis is a safe and effective method of treating lower limb ischaemia in selected patients. It allows for a decrease in the total dose of the thrombolytic agent and can be a good alternative to surgical procedure.
Keywords
arterial thrombosis; graft thrombosis; intra-arterial thrombolysis
About this articleTitle
Local intra-arterial thrombolysis for peripheral arterial occlusion
Journal
Issue
Article type
Research paper
Pages
14-23
Published online
2005-01-14
Page views
770
Article views/downloads
2089
DOI
10.5603/aa.9898
Bibliographic record
Acta Angiologica 2005;11(1):14-23.
Keywords
arterial thrombosis
graft thrombosis
intra-arterial thrombolysis
Authors
Tadeusz Mularczyk
Waldemar Kostewicz
Jan Purtak
Władysław Wiśniewski