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The usefulness of assessing the serum levels of homocysteine in diagnosis of atherosclerosis
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Abstract
Material and methods. Sixty-eight patients including 26 with lower extremities atherosclerosis, 10 after CABG, 10 with AMI, 15 with ischemic stroke, 4 with abdominal aortic aneurysm and 3 with renal artery obstruction were enrolled. Patients suffering from acute MI or stroke, kidney failure, autoimmune diseases and neoplasms were excluded from the investigation. Thirty healthy volunteers were the control group.
Results. Homocysteine levels in all patient groups were higher than in the control group except patients with abdominal aortic aneurysm. The highest homocysteine concentrations (29.2 ± 11.32 µmol/l; p < 0.001) were in patients after CABG.
Conclusions. homocysteine is an important, independent cardiovascular diseases risk factor and should be routinely examined for in patients with other risk factors.
Abstract
Material and methods. Sixty-eight patients including 26 with lower extremities atherosclerosis, 10 after CABG, 10 with AMI, 15 with ischemic stroke, 4 with abdominal aortic aneurysm and 3 with renal artery obstruction were enrolled. Patients suffering from acute MI or stroke, kidney failure, autoimmune diseases and neoplasms were excluded from the investigation. Thirty healthy volunteers were the control group.
Results. Homocysteine levels in all patient groups were higher than in the control group except patients with abdominal aortic aneurysm. The highest homocysteine concentrations (29.2 ± 11.32 µmol/l; p < 0.001) were in patients after CABG.
Conclusions. homocysteine is an important, independent cardiovascular diseases risk factor and should be routinely examined for in patients with other risk factors.
Keywords
homocysteine; atherosclerosis; intermittent claudication; coronary artery bypass; myocardial infarction; brain infarction; renal artery obstruction; aortic aneurysm; abdominal
About this articleTitle
The usefulness of assessing the serum levels of homocysteine in diagnosis of atherosclerosis
Journal
Issue
Article type
Research paper
Pages
114-120
Published online
2005-05-19
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1111
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1612
Bibliographic record
Acta Angiologica 2005;11(2):114-120.
Keywords
homocysteine
atherosclerosis
intermittent claudication
coronary artery bypass
myocardial infarction
brain infarction
renal artery obstruction
aortic aneurysm
abdominal
Authors
Danuta Kokocińska
Lech Cierpka
Bogdan Chmiel
Marian Duraj
Robert Partyka
Szymon Cierpka
Jacek Kocot
Piotr Wieczorek