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Prosthetic graft infection treated by local surgery - comparative analysis of 64 consecutive cases
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Abstract
Material and methods. In the years 1996–2003 sixty-four patients with prosthetic infection were treated by local therapy or partial removal of the graft.
Results. During the observation period, 5% of the patients died and in 7.5% limb amputation was necessary. 92.4% of the patients were primarily cured of their infection but at follow up only 38.7% patients had healed satisfactorily without symptoms of reinfection. Symptoms of reinfection appeared in 53.7% patients within 1–36 months. The infection symptoms recurrence was observed most seldom in patients group after partial removal of the prosthesis without blood vessel reconstruction. Despite 5 cases of the recurrence limited to the groin responding to local therapy techniques, all other cases resulted in the progress of infection.
Conclusions. Local treatment carries a high risk of reinfection, and should only be used for culture-negative grafts or in individuals who do not accept more radical treatment. Irrespective of the treatment method used the patients should be kept under regular clinical and radiological review for the early detection of reinfection diagnosis and the application of a more radical treatment approach.
Abstract
Material and methods. In the years 1996–2003 sixty-four patients with prosthetic infection were treated by local therapy or partial removal of the graft.
Results. During the observation period, 5% of the patients died and in 7.5% limb amputation was necessary. 92.4% of the patients were primarily cured of their infection but at follow up only 38.7% patients had healed satisfactorily without symptoms of reinfection. Symptoms of reinfection appeared in 53.7% patients within 1–36 months. The infection symptoms recurrence was observed most seldom in patients group after partial removal of the prosthesis without blood vessel reconstruction. Despite 5 cases of the recurrence limited to the groin responding to local therapy techniques, all other cases resulted in the progress of infection.
Conclusions. Local treatment carries a high risk of reinfection, and should only be used for culture-negative grafts or in individuals who do not accept more radical treatment. Irrespective of the treatment method used the patients should be kept under regular clinical and radiological review for the early detection of reinfection diagnosis and the application of a more radical treatment approach.
Keywords
arterial prosthetic; graft infection; local therapy; reinfection; revascularization; debridement
About this articleTitle
Prosthetic graft infection treated by local surgery - comparative analysis of 64 consecutive cases
Journal
Issue
Article type
Research paper
Pages
167-179
Published online
2006-11-24
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953
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1843
Bibliographic record
Acta Angiologica 2006;12(4):167-179.
Keywords
arterial prosthetic
graft infection
local therapy
reinfection
revascularization
debridement
Authors
Marcin Gabriel
Grzegorz Oszkinis
Michał Stanišić
Katarzyna Pawlaczyk
Zbigniew Krasiński
Łukasz Dzieciuchowicz
Robert Juszkat
Maciej Zieliński