Atherosclerosis: How far we have gone?

Abstract

This review will attempt to provide a database of knowledge regarding the atherosclerosis pathology and its mechanisms in order to better understand the complexity of this process. Atherosclerosis remains a real problem not only for patients suffering from eg. peripheral arteries disease (PAD) but also for physicians and researchers as well. Based on the multidisciplinary research that has been carried out, we can see this process has become more complicated than we saw in the past few decades. The role of angiogenesis, vasa vasorum, growth factors, dendritic cells, inflammation and/or infection has been noticed.